Modulating immunometabolism in transition dairy cows: the role of inflammatory lipid mediators.

Abstract

(e.g., hormone-sensitive lipase). Polyunsaturated fatty acids are then oxidized by cyclooxygenases, lipooxygenases, and cytochrome P450 (CYP450) enzymes to produce oxylipids. Among these, the immunometabolic effects of prostaglandins, thromboxanes, hydroxyeicosatetraenoic (HETE), and hydroxyoctadecadienoic (HODE) acids are characterized in transition dairy cows.