Targeting Three Brain Regions (Bilateral SMA, Left and Right DLPFC) Sequentially in One Session Using Combined Repetitive Transcranial Magnetic Stimulation and Intermittent Theta-burst Stimulation in Treatment-refractory Obsessive-compulsive Disorder: A Case Report.

IF 2.4 4区医学 Q3 NEUROSCIENCES

Clinical Psychopharmacology and Neuroscience Pub Date : 2022-11-30 DOI:10.9758/cpn.2022.20.4.773

Po-Han Chou, Alexander T Sack, Kuan-Pin Su

引用次数: 3

Abstract

Repetitive transcranial magnetic stimulation (rTMS) has been widely used as a therapy for refractory obsessive-compulsive disorder (OCD). However, it remains unclear which exact target and stimulation sequence of rTMS is most effective for OCD. Here, we report the case of an 18-year-old female with treatment-refractory OCD whose symptoms markedly improved after combined rTMS and intermittent theta-burst stimulation over the bilateral dorsolateral prefrontal cortex and supplementary motor area. Our report indicates that combining treatment sequences that stimulate different brain regions sequentially is feasible and may clinically benefit patients suffering from OCD.

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重复性经颅磁刺激和间歇性Theta爆裂刺激联合治疗难治性强迫症，一次治疗中依次靶向三个脑区（双侧SMA、左右DLPFC）：一例报告。

重复经颅磁刺激(rTMS)已被广泛用于治疗难治性强迫症(OCD)。然而，目前尚不清楚rTMS的确切靶点和刺激顺序对强迫症最有效。在此，我们报告一名18岁的女性强迫症患者，在双侧背外侧前额皮质和辅助运动区进行rTMS和间歇性脑波爆发刺激后，其症状明显改善。我们的报告表明，依次刺激不同大脑区域的组合治疗序列是可行的，并且可能在临床上使患有强迫症的患者受益。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Psychopharmacology and Neuroscience NEUROSCIENCESPHARMACOLOGY & PHARMACY-PHARMACOLOGY & PHARMACY

CiteScore

4.70

自引率

12.50%

发文量

期刊介绍： Clinical Psychopharmacology and Neuroscience (Clin Psychopharmacol Neurosci) launched in 2003, is the official journal of The Korean College of Neuropsychopharmacology (KCNP), and the associate journal for Asian College of Neuropsychopharmacology (AsCNP). This journal aims to publish evidence-based, scientifically written articles related to clinical and preclinical studies in the field of psychopharmacology and neuroscience. This journal intends to foster and encourage communications between psychiatrist, neuroscientist and all related experts in Asia as well as worldwide. It is published four times a year at the last day of February, May, August, and November.