Supervised exercises have superior effects compared to home-based exercises for patients with knee osteoarthritis following platelet-rich plasma injection.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-03-01 Epub Date: 2022-07-19 DOI:10.1080/15438627.2022.2102920

Sibel Bozgeyik, Gizem Irem Kinikli, Yusuf Topal, Muharrem Gökhan Beydagi, Egemen Turhan, Hasan Erkan Kilinç, Hande Güney-Deniz

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引用次数: 1

Abstract

The purpose of the study was to compare the effectiveness of physiotherapist-supervised and home-based exercises after platelet-rich-plasma (PRP) injection in knee osteoarthritis (OA). Thirty women (mean age = 57.83 ± 7.26 years; mean weight = 72.13 ± 15.54 kg; mean height = 158.40 ± 4.49 cm; mean body mass index = 28.75 ± 6.18 kg/m²) were included. Patients randomized either supervised or home-basedexercise-group after PRP. Both groups performed 6-week (3 times/week) exercise. Pain, hip and knee muscle strength, and knee functions were assessed before and after exercise. The median improvement in the pain from baseline to 6^th week was 3.80 (2.85-5.55) point in-supervised-exercise-group while it was 0.60 (-0.10-2.55) point in home-based-exercise-group (p = 0.002). The median improvement in knee function was 22.91 (13.02-30.20) in supervised-exercise-group overtime (p < 0.001). There was no improvement in knee function following home-based exercises (p = 1.000). The supervised-exercise-group revealed a significant improvement in hip (median difference = 32.00 (8.30-88.95), p = 0.011); quadriceps (median difference = 32.10 (21.65-60.05), p = 0.001) and hamstring (median difference = 27.90 (7.95-37.65), p = 0.022) strength overtime. The physiotherapist-supervised exercises after PRP had better effects on pain and knee function than the home-based exercises.

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对注射富血小板血浆后的膝关节骨关节炎患者而言，在指导下进行锻炼的效果优于在家中进行锻炼。

本研究旨在比较膝关节骨性关节炎（OA）患者在注射血小板丰富血浆（PRP）后，在理疗师指导下进行锻炼和在家进行锻炼的效果。研究对象包括 30 名女性（平均年龄为 57.83 ± 7.26 岁；平均体重为 72.13 ± 15.54 千克；平均身高为 158.40 ± 4.49 厘米；平均体重指数为 28.75 ± 6.18 千克/平方米）。患者在接受 PRP 治疗后，随机分为监督锻炼组或家庭锻炼组。两组患者均进行为期 6 周（每周 3 次）的锻炼。运动前后对疼痛、髋关节和膝关节肌力以及膝关节功能进行了评估。从基线到第 6 周，监督锻炼组疼痛改善的中位数为 3.80（2.85-5.55）点，而在家锻炼组为 0.60（-0.10-2.55）点（P = 0.002）。督导锻炼组的膝关节功能改善中位数为 22.91（13.02-30.20）分（p = 0.002）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.