Imaging Features of Lymphoepithelial-Like Carcinoma of the Salivary Glands.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2025-07-01 Epub Date: 2022-07-17 DOI:10.1177/01455613221116330
Meng Zhang, Jingzhi Ye, Hongyi Li, Peikai Huang, Jun Chen, Fenghuang Lin, Mengqiang Xiao
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引用次数: 0

Abstract

Objective: Lymphoepithelial-like carcinoma of the salivary glands (LELCSG) is a rare tumour of unknown aetiology. No studies have reported the imaging features of primary LELCSG.

Methods: The clinical information and imaging features of eight patients with LELCSG were reviewed. Computed tomography (n = 4 patients) and magnetic resonance imaging (n = 4 patients) features were analysed by two radiologists to identify the location, number, size, shape, boundary, signal intensity and enhancement of LELCSG.

Results: The study included four women and four men, and the mean size of the tumours was 32.88 ± 3.41 mm (range, 27-38 mm). The tumours affected the parotid gland in six cases and the submandibular gland in two cases. The eight cases were evaluated by radiologists. All tumours were lobulated; three had clear edges and five had blurred edges. There was no necrosis in six tumours, while two tumours exhibited slight necrosis without bleeding. All eight tumours showed multiple nodular changes and extensive fusion. Four tumours with magnetic resonance imaging (MRI) were isointense or slightly hyperintense on T1-weighted imaging (T1WI) and obvious homogeneous enhancement on contrasted enhanced T1WI scan, while slightly hyperintense on T2-weighted imaging (T2WI). The other four lesions were isodense on computed tomography (CT) scan. The degree of enhancement varied among the eight tumours. The necrotic zones of the eight tumours did not exhibit any enhancement.

Conclusions: LELCSG is a lobulated, multi-nodular tumour, with some fused nodules. LELCSG lesions showed isointensity or slight hyperintensity on T1WI MRI, slight hyperintensity on T2WI MRI and isodense on CT scan. Larger tumours may exhibit some necrosis, but the necrotic cysts were relatively rare. Uniform enhancement was observed in non-necrotic areas on enhanced CT and MRI scan. The multi-nodular feature may be valuable for diagnosis.

唾液腺淋巴上皮样癌的影像学特征。
目的:唾液腺淋巴上皮样癌(LELCSG唾液腺淋巴上皮样癌(LELCSG)是一种病因不明的罕见肿瘤。目前还没有研究报告原发性唾液腺淋巴上皮样癌的影像学特征:方法:研究人员回顾了8例LELCSG患者的临床信息和影像学特征。由两名放射科医生对计算机断层扫描(n = 4 名患者)和磁共振成像(n = 4 名患者)特征进行分析,以确定 LELCSG 的位置、数量、大小、形状、边界、信号强度和增强情况:研究包括四名女性和四名男性,肿瘤的平均大小为 32.88 ± 3.41 毫米(范围为 27-38 毫米)。肿瘤累及腮腺的有 6 例,累及颌下腺的有 2 例。八例肿瘤均由放射科医生进行了评估。所有肿瘤均呈分叶状,其中三例边缘清晰,五例边缘模糊。六个肿瘤没有坏死,两个肿瘤有轻微坏死,但没有出血。所有 8 个肿瘤均呈多发性结节变化和广泛融合。四个肿瘤的磁共振成像(MRI)在T1加权成像(T1WI)上呈等密度或轻度高密度,在对比增强的T1WI扫描上呈明显的均匀强化,而在T2加权成像(T2WI)上呈轻度高密度。其他四个病灶在计算机断层扫描(CT)中呈等密度。八个肿瘤的增强程度各不相同。这八个肿瘤的坏死区没有任何强化:结论:LELCSG是一种分叶状、多结节肿瘤,其中有一些融合结节。LELCSG病变在T1WI磁共振成像上显示等密度或轻微高密度,在T2WI磁共振成像上显示轻微高密度,在CT扫描上显示等密度。较大的肿瘤可能会出现一些坏死,但坏死囊肿相对较少。在增强 CT 和 MRI 扫描中,非坏死区域呈均匀强化。多结节特征可能对诊断有价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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