Comparative pharmacognosy and phytochemical evaluation of leaf, root and stem of Psoralea corylifolia Linn. (Bakuchi).

Ayu Pub Date : 2020-10-01 Epub Date: 2022-06-03 DOI:10.4103/ayu.ayu_79_21
Sarika Makwana, Nikhil Mehere, Prashant Bedarkar, Patgiri Biswajyoti, C R Harisha
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引用次数: 1

Abstract

Background: Psoralea corylifolia Linn. (P. Corylifolia L.), frequently familiar as Bakuchi in Samskrit, is an endangered and medicinally important plant. Its medicinal usage is reported in Indian pharmaceutical codex, the Chinese, British and the American Pharmacopoeia, and in different traditional systems of medicines such as Ayurveda, Unani and Siddha. However, no scientifically pharmacognosy study has been reported on leaf, root, and stem part of P. Corylifolia L. Classics emphasized the use of leaf, root and stem of P. Corylifolia L. for on the management of dental carries, diarrhea, dysentery, etc., in the form of local application as well as internal administration.

Aim: The aim of this study was to evaluate comparative pharmacognosy, phytochemical studies, and physicochemical analysis of leaf, root and stem of P. Corylifolia L.

Materials and methods: Studies of leaf, root, stem, and their powder for phytochemical tests, histochemical tests, psoralen chemical test, and physicochemical analysis were performed by standard methods.

Result: All the different parts of the plant exhibit oleoresin and other cellular contents, i.e., vessels fibers, lignified pitted vessels, etc., in pharmacognosy studies. In phytochemical study; observations indicate that coumarins, steroids, and flavonoids are present in leaf, stem, and root samples. Basified alcoholic extracts of powders of all test samples showed yellowish color of fluorescence at 366 nm whereas none of the samples showed any color at 254 nm during chemical test of psoralen.

Conclusion: Pharmacognostical study on leaf, root and stem of Bakuchi (P. corylifolia L.) contributed Certain pharmacognostical parameters i.e; oleoresin, vascular bundles, parenchyma cells with rhomboidal crystals, pericyclic fibres etc parameters that will be applicable for authentication and identification of the parts of drug. There is a need to focus on the preliminary throughput phytochemical screening of plants for their probable use in therapeutics. As no published evidences are developed on comparative pharmacognosy and preliminary physicochemical analysis of leaf, root and stem of P. corylifolia L. plant, the results documented in the present study may be used as a standard in subsequent studies. These observations can be of use for further research studies.

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补骨脂叶、根、茎的比较生药学及植物化学评价。(Bakuchi)。
背景:补骨脂。(P. Corylifolia L.),在Samskrit经常被称为Bakuchi,是一种濒危的重要药用植物。印度药典、中国、英国和美国药典以及不同的传统药物体系(如阿育吠陀、乌纳尼和悉达)都报道了它的药用价值。然而,目前还没有对雪兰叶、根、茎部分进行科学生药学研究的报道。经典文献强调雪兰叶、根、茎用于治疗牙病、腹泻、痢疾等,既可局部应用,也可内服。目的:对雪兰叶、根、茎的比较生药学、植物化学研究和理化分析进行评价。材料和方法:采用标准方法对雪兰叶、根、茎及其粉末进行植物化学试验、组织化学试验、补骨脂素化学试验和理化分析。结果:在生药学研究中,该植物的所有不同部位均表现出油树脂和其他细胞内容物,即血管纤维、木质素化的凹陷血管等。植物化学研究;观察表明香豆素、类固醇和类黄酮存在于叶、茎和根样品中。在补骨脂素化学测试中,所有样品粉末的碱化酒精提取物在366 nm处显示淡黄色荧光,而在254 nm处没有样品显示任何颜色。结论:竹叶、根、茎的生药学研究提供了一定的生药学参数;油树脂、维管束、含菱形晶体的薄壁细胞、周环纤维等参数,适用于药品成分的鉴别和鉴定。有必要把重点放在植物的初步通量植物化学筛选上,以便它们可能用于治疗。由于在比较生药学和叶、根、茎的初步理化分析方面尚无文献发表,本研究结果可作为后续研究的参考依据。这些观察结果可用于进一步的研究。
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