Smallpox vaccination discontinuation and monkeypox incidence in an African endemic region: a reanalysis on the relationship between the withdrawal of smallpox vaccine and subsequent morbidity.

IF 1.4 Q4 IMMUNOLOGY
American journal of clinical and experimental immunology Pub Date : 2022-10-15 eCollection Date: 2022-01-01
Rujittika Mungmunpuntipantip, Viroj Wiwanitkit
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Abstract

Background: Monkey pox has expanded across Europe as a result of the widespread outbreak, creating a severe public health risk. Monkey pox is an uncommon pox infection that has reappeared due to zoonosis. Monkey pox has spread over Europe and North America, posing a serious public health risk. The regular smallpox vaccine has been shown to be effective against monkeypox. The suspension of smallpox immunization is currently being debated due to the possibility of a connection with the current monkeypox outbreak. In clinical immunology, the link between a desire for smallpox vaccination, low population immunity, and a higher incidence of monkeypox is an intriguing topic.

Methods: This is a descriptive analysis done in the past. The writers investigate the situation in West Africa in this research. The available data on monkeypox incidence in an African endemic area was reassessed.

Results: Based on a recent analysis of epidemiological data from an endemic area, there is no indication of a yearly ongoing increase in monkeypox incidence following the discontinuation of the smallpox vaccine, and incidence varies.

Conclusion: There is no evidence of an annual increase in monkeypox incidence following the withdrawal of smallpox immunization.

非洲某流行区停止接种天花疫苗与猴痘发病率:对停止接种天花疫苗与随后发病率关系的再分析
背景:由于猴痘大范围暴发,它已在整个欧洲蔓延,造成严重的公共卫生风险。猴痘是一种罕见的因人畜共患病而重新出现的痘感染。猴痘已蔓延到欧洲和北美,构成严重的公共卫生风险。常规天花疫苗已被证明对猴痘有效。目前正在讨论暂停天花免疫接种的问题,因为这可能与当前猴痘疫情有关。在临床免疫学中,希望接种天花疫苗、人群免疫力低下和猴痘发病率较高之间的联系是一个有趣的话题。方法:这是过去所做的描述性分析。作者在这项研究中调查了西非的情况。重新评估了一个非洲流行区猴痘发病率的现有数据。结果:根据最近对一个流行区流行病学数据的分析,没有迹象表明在停止接种天花疫苗后猴痘发病率每年持续增加,而且发病率各不相同。结论:没有证据表明在取消天花免疫接种后猴痘发病率每年增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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