Does the Duration of the Illness Affect the Severity of Negative Symptoms of Schizophrenia?

Materia Socio-Medica Pub Date : 2022-03-01 DOI:10.5455/msm.2022.33.25-27

Nejra Becarevic, Rusmir Softic, Enes Osmanovic

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引用次数: 2

Abstract

Background: The negative symptoms of schizophrenia are less known aspects of the illness although they often mark its course and outcome. Negative symptoms refer to loss of function, and they are associated with poor outcomes. It is considered that they are more prominent with the longer duration of illness.

Objective: To determine the negative symptoms in the patients with schizophrenia with regard to the duration of illness.

Methods: A cross-sectional study was conducted in 60 consecutive outpatients with schizophrenia. Two groups were formed regarding the duration of illness (⩽2 years, and >3 years). The negative symptoms were established with the Brief Negative Symptom Assessment - BNSA.

Results: Average score of negative symptoms in the group with the shorter duration of illness was 8.37±2.94, and in the group with longer duration was 10.73±2.86. Independent Samples Test was significant p=0.003, t-2.367, and therefore the difference between scores on BNSA within groups was significant. Moderate size effect was found (p = 0.69).

Conclusion: Negative symptoms of schizophrenia are more prominent with the longer duration of illness.

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病程是否影响精神分裂症阴性症状的严重程度?

背景:精神分裂症的阴性症状是该疾病鲜为人知的方面，尽管它们通常标志着其过程和结果。阴性症状是指功能丧失，与不良预后相关。据认为，它们随着病程的延长而更加突出。目的:了解精神分裂症患者的阴性症状与病程的关系。方法:对60例精神分裂症门诊患者进行横断面研究。按病程分为两组(≥2年和>3年)。阴性症状采用简短阴性症状评估- BNSA确定。结果:病程较短组阴性症状平均得分为8.37±2.94分，病程较长组阴性症状平均得分为10.73±2.86分。独立样本检验p=0.003, t-2.367，组内BNSA得分差异显著。存在中等大小效应(p = 0.69)。结论:精神分裂症的阴性症状随着病程的延长而更加突出。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Materia Socio-Medica

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