Current status of acute ischemic stroke management in Iran: Findings from a single-center study.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2022-09-30 eCollection Date: 2022-10-01 DOI:10.4103/2452-2473.357344

Hesamedin Askari-Majdabadi, Zahra Basereh, Amin Soheili, Kelly Powers, Mohsen Soleimani, Majid Mirmohammdkhani, Tahoura Afshari Saleh

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引用次数: 1

Abstract

Objectives: This study investigated the current status of acute ischemic stroke (AIS) management in an Iranian emergency department (ED).

Methods: A descriptive study using a retrospective chart review was conducted on medical records of 270 patients with AIS who presented to the ED of a tertiary university hospital in the northeast of Iran from March 22 to September 22, 2019. The steps of this review process included instrument identification, medical records retrieval, data extraction, and data verification.

Results: Of patients with AIS, 88.9% (n = 240) did not receive stroke code activation. For the 11.1% of patients (n = 30) who received activation, 7% of codes (n = 19) were canceled by the acute stroke team and IV recombinant tissue plasminogen activator (r-tPA) was only administered for 4.1% of patients (n = 11). ED arrival outside 4.5 h from symptom onset was the main barrier to IV r-tPA administration for 83.8% of potentially eligible patients with AIS (n = 217). The median door-to-needle time was 70 min (interquartile range: 47-90 min).

Conclusions: There was a better clinical performance in terms of critical time goals in potentially eligible patients with AIS if managed with stroke team activation compared to no stroke team activation.

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伊朗急性缺血性脑卒中管理现状:一项单中心研究的结果

目的:本研究调查了伊朗急诊科(ED)急性缺血性卒中(AIS)管理的现状。方法:对2019年3月22日至9月22日在伊朗东北部某三级大学医院急诊科就诊的270例AIS患者的病历进行回顾性图表复习的描述性研究。该审查过程的步骤包括仪器识别、医疗记录检索、数据提取和数据验证。结果:在AIS患者中，88.9% (n = 240)未接受脑卒中代码激活。在接受激活的11.1%的患者(n = 30)中，7%的代码(n = 19)被急性卒中团队取消，只有4.1%的患者(n = 11)使用了重组组织型纤溶酶原激活剂(r-tPA)。83.8%的潜在符合条件的AIS患者(n = 217)在症状出现后4.5小时内出现ED是静脉注射r-tPA的主要障碍。门到针的中位时间为70 min(四分位数间距为47 ~ 90 min)。结论:与没有卒中团队激活相比，卒中团队激活管理的潜在符合条件的AIS患者在关键时间目标方面有更好的临床表现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.