Characterization of the human gut virome in metabolic and autoimmune diseases.

IF 5 3区医学 Q2 IMMUNOLOGY

Inflammation and Regeneration Pub Date : 2022-11-01 DOI:10.1186/s41232-022-00218-6

Kosuke Fujimoto, Daichi Miyaoka, Satoshi Uematsu

引用次数: 2

Abstract

The intestinal microbiome is dominated by bacteria and plays a pivotal role in the occurrence and development of disease, including several metabolic and autoimmune disorders. While intestinal viral communities, primarily made up of bacteriophages, are also thought to play a role in disease pathogenesis in the gastrointestinal tract, they have received much less attention than intestinal bacteria. Thus, there is limited information about the relationship between bacteriophages and disease. This review explores a potential role for the intestinal viral microbiome in various metabolic and autoimmune diseases.

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代谢性和自身免疫性疾病中人类肠道病毒的特征。

肠道微生物群由细菌主导，在疾病的发生和发展中起着关键作用，包括几种代谢和自身免疫性疾病。虽然主要由噬菌体组成的肠道病毒群落也被认为在胃肠道疾病发病机制中发挥作用，但它们受到的关注远不及肠道细菌。因此，关于噬菌体与疾病之间关系的信息有限。这篇综述探讨了肠道病毒微生物组在各种代谢和自身免疫性疾病中的潜在作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Inflammation and Regeneration Multiple-

CiteScore

11.10

自引率

1.20%

发文量

审稿时长

11 weeks

期刊介绍： Inflammation and Regeneration is the official journal of the Japanese Society of Inflammation and Regeneration (JSIR). This journal provides an open access forum which covers a wide range of scientific topics in the basic and clinical researches on inflammation and regenerative medicine. It also covers investigations of infectious diseases, including COVID-19 and other emerging infectious diseases, which involve the inflammatory responses. Inflammation and Regeneration publishes papers in the following categories: research article, note, rapid communication, case report, review and clinical drug evaluation.