Comparison of cartilage and temporalis fascia grafts in type 1 tympanoplasty: A meta-analysis.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2025-08-01 Epub Date: 2022-10-27 DOI:10.1177/01455613221137122
Kai Chen, Rui Zhao
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引用次数: 0

Abstract

ObjectiveTo systematically review the results of type 1 tympanoplasties with temporalis fascia (TF) vs cartilage grafts in patients with chronic otitis media.MethodsEligible studies were identified from PubMed, Ovid, and EMBASE databases prior to November 2021. We analyzed the pure tone audiometry (PTA) and air-bone gap (ABG) data as continuous variables, and the success rate was analyzed as a dichotomous variable.ResultsForty-four studies, including 4582 patients, were eligible. The cartilage graft overall morphologic success rate was higher than that of the TF grafts (P < .001). In the palisade (P < .004) and island grafts (P < .001) subgroups, the analysis was significantly different. However, there was no significant difference in the inlay butterfly grafts subgroup. For hearing outcomes, the analysis revealed that TF grafts had a smaller mean post-operative ABG (P = .009). However, the subgroup analysis showed no significant difference in the mean post-operative ABG. For PTA, there was no significant difference in hearing improvement. However, the palisade cartilage graft subgroup resulted in a better hearing outcome than the TF graft subgroup in terms of the mean post-operative PTA (P = .007). There was no significant difference in the functional success rate or mean ABG gain.ConclusionCartilage grafts have a better success rate than TF grafts in tympanoplasty. Both cartilage and TF tympanoplasty provided similar improvements in hearing outcome, while TF grafts generated a better outcome in post-operative ABG and palisade cartilage grafts in post-operative PTA. This may be related to the biological characteristics of the grafts. Further thorough studies need to be conducted.

1型鼓室成形术中软骨与颞筋膜移植的比较:荟萃分析
目的系统回顾慢性中耳炎患者使用颞筋膜(TF)与软骨移植的1型鼓室成形术的结果:从 2021 年 11 月之前的 PubMed、Ovid 和 EMBASE 数据库中筛选出符合条件的研究。我们将纯音测听(PTA)和气骨间隙(ABG)数据作为连续变量进行分析,将成功率作为二分变量进行分析:结果:44 项研究(包括 4582 名患者)符合条件。软骨移植物的总体形态学成功率高于TF移植物(P < .001)。在腭状移植物(P < .004)和岛状移植物(P < .001)亚组中,分析结果有显著差异。但是,镶嵌式蝶形移植物亚组没有明显差异。在听力结果方面,分析显示 TF 移植物的术后平均 ABG 较小(P = .009)。但是,亚组分析显示术后平均 ABG 没有显著差异。对于 PTA,听力改善方面没有明显差异。不过,就术后平均 PTA 而言,姑息软骨移植亚组的听力结果优于 TF 移植亚组(P = .007)。在功能成功率或平均 ABG 增益方面没有明显差异:结论:在鼓室成形术中,软骨移植物的成功率高于TF移植物。结论:在鼓室成形术中,软骨移植物比 TF 移植物的成功率更高。软骨鼓室成形术和 TF 鼓室成形术在改善听力方面的效果相似,而 TF 移植物在术后 ABG 方面的效果更好,姑息软骨移植物在术后 PTA 方面的效果更好。这可能与移植物的生物特性有关。还需要进行更深入的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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