Immunomodulatory Effects of Vitamin D and Prevention of Respiratory Tract Infections and COVID-19.

IF 0.4 4区 医学 Q4 NUTRITION & DIETETICS
Topics in Clinical Nutrition Pub Date : 2022-07-01 Epub Date: 2022-06-22 DOI:10.1097/TIN.0000000000000284
Marni E Shoemaker, Linda M Huynh, Cory M Smith, Vikkie A Mustad, Maria O Duarte, Joel T Cramer
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引用次数: 1

Abstract

Little is known about potential protective factors for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), referred to as COVID-19. Suboptimal vitamin D status is a risk factor for immune dysfunction, respiratory tract infections (RTIs), and viral infections. Supplementation of vitamin D (2000-4000 IU) has decreased incidence and complications from RTIs, respiratory distress syndrome, and pneumonia and may be beneficial in high-risk populations. Given the possible link between low vitamin D status and RTIs, such as COVID-19, this review examined whether vitamin D supplementation can be supported as a nutritional strategy for reducing risk of infection, complications, and mortality from COVID-19 and found that the relationship between vitamin D and RTIs warrants further exploration.

维生素D的免疫调节作用和预防呼吸道感染和新冠肺炎。
对严重急性呼吸综合征冠状病毒2(SARS-CoV-2)(称为新冠肺炎)的潜在保护因素知之甚少。次优维生素D状态是免疫功能障碍、呼吸道感染和病毒感染的风险因素。补充维生素D(2000-4000IU)可降低RTI、呼吸窘迫综合征和肺炎的发病率和并发症,对高危人群可能有益。鉴于维生素D水平低与RTI(如新冠肺炎)之间的可能联系,本综述研究了维生素D补充是否可以作为降低新冠肺炎感染、并发症和死亡率风险的营养策略,并发现维生素D与RTI之间的关系值得进一步探索。
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来源期刊
Topics in Clinical Nutrition
Topics in Clinical Nutrition NUTRITION & DIETETICS-
CiteScore
0.90
自引率
20.00%
发文量
34
期刊介绍: ​​Topics in Clinical Nutrition (TICN) is a peer-reviewed, quarterly journal designed as a resource for the continuing education and clinical practice of dietitians and nutritionists. Each issue addresses topics of interest primarily to dietitians and nutritionists, students and interns in professional training programs and other health care personnel involved in the nutritional care of patients. Articles include translational research reports (work that applies new knowledge to practical effect), practice projects, evidence-based literature reviews, case studies and book reviews, and articles that highlight education theory and applied research which share the tools and techniques of nutrition and dietetics education.
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