Effect of combined aerobic and resistance exercise on serum Klotho secretion in healthy young men -a pilot study-

IF 2.1 Q3 PHYSIOLOGY
Takuma Morishima , Eisuke Ochi
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引用次数: 1

Abstract

The impact of combined aerobic and resistance exercise on Klotho (KL) secretion is unclear. Twelve healthy young men completed two randomized experimental trials: 1) resistance exercise (RE) and 2) resistance exercise with prior aerobic exercise (AE + RE). Following baseline blood pressure assessment and blood collection, the subjects in the RE trial maintained a supine position for 45 min, while the subjects in the AE + RE trial performed 45 min of aerobic exercise. After 45 min of resting or aerobic exercise, all subjects performed resistance exercise. Following resistance exercise, the subjects rested in a supine position for 60 min. Blood pressure assessment and blood collection were repeated. Aerobic and resistance exercise significantly increased serum KL concentrations, respectively (P < 0.05), and no additive effect of aerobic exercise on KL secretion was observed immediately after resistance exercise in the AE + RE trial compared with the RE trial. However, serum KL levels at 30 and 60 min after resistance exercise were significantly higher in the AE + RE trial than in the RE trial. Serum ET-1 concentrations were significantly increased only in the RE trial. In conclusion, combined aerobic and resistance exercise could maintain higher levels of serum KL secretion after exercise compared with resistance exercise only.

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有氧与抗阻联合运动对健康青年男性血清Klotho分泌影响的初步研究
有氧和阻力联合运动对Klotho (KL)分泌的影响尚不清楚。12名健康的年轻男性完成了两项随机实验:1)阻力运动(RE)和2)阻力运动加有氧运动(AE + RE)。在基线血压评估和采血后,RE组受试者保持仰卧位45分钟,AE + RE组受试者进行有氧运动45分钟。在休息或有氧运动45分钟后,所有受试者进行阻力运动。阻力运动后,受试者仰卧休息60分钟。重复血压评估和采血。有氧运动和阻力运动分别显著提高血清KL浓度(P <在AE + RE试验中,与RE试验相比,阻力运动后立即进行有氧运动对KL分泌没有加性影响。然而,在阻力运动后30和60分钟,AE + RE试验的血清KL水平明显高于RE试验。血清ET-1浓度仅在RE试验中显著升高。综上所述,有氧与抗阻联合运动比单纯抗阻运动能维持较高的运动后血清KL分泌水平。
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来源期刊
CiteScore
3.20
自引率
0.00%
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审稿时长
62 days
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