Trends of Alcohol Withdrawal Delirium in the Last Decade: Analysis of the Nationwide Inpatient Sample.

IF 1.4 Q4 GASTROENTEROLOGY & HEPATOLOGY
Gastroenterology Research Pub Date : 2022-08-01 Epub Date: 2022-08-23 DOI:10.14740/gr1550
Hisham Laswi, Bashar Attar, Robert Kwei, Pius Ojemolon, Ebehiwele Ebhohon, Hafeez Shaka
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引用次数: 1

Abstract

Background: Alcohol use disorder, high-risk drinking, and emergency visits for acute and chronic complications of alcohol use have been increasing in the USA recently. Approximately half of patients with alcohol use disorder experience alcohol withdrawal when they reduce or stop drinking. Though alcohol withdrawal is usually mild, 20% of patients experience more severe manifestations such as hallucinations, seizures, and delirium. In this study, we utilized the Nationwide Inpatient Sample to examine the trends of alcohol withdrawal delirium (AWD) in the period 2010 - 2019.

Methods: This was a retrospective longitudinal trends study involving hospitalizations with AWD in the USA from 2010 to 2019. We searched the databases for hospitalizations using the International Classification of Diseases (ICD) codes (291.0 and F10231). We involved all hospitalizations complicated by AWD and hospitalizations with AWD as the principal diagnosis for admission. We excluded hospitalizations involving patients under the age of 18. We calculated the crude admission rate and the incidence of AWD per million adult hospitalizations during each calendar year. In addition, we analyzed trends of inpatient mortality, length of stay (LOS), and total hospital charges (THC).

Results: The incidence of AWD per million hospitalizations increased from 2,671.8 in 2010 to 3,405.6 in 2019, with an annual percentage change (APC) of 3.1% (P < 0.001). Similarly, AWD admission rate per million hospitalizations increased from 1,030.3 in 2010 to 1,556.0 in 2019, with an average APC of 5.0% (P < 0.001). There were statistically significant trends of increasing inpatient mortality, THC, and LOS over the studied period. In general, female gender, younger age, and Black race were associated with better clinical outcomes.

Conclusions: Our study showed an increase in the incidence and admission rates of AWD. Mortality, LOS, and THC increased over the studied period. Younger age, female gender, and Black race were associated with better clinical outcomes.

Abstract Image

Abstract Image

近十年来酒精戒断性谵妄的趋势:全国住院患者样本分析。
背景:最近在美国,酒精使用障碍、高风险饮酒和因酒精使用急性和慢性并发症而急诊就诊的人数不断增加。大约一半的酒精使用障碍患者在减少或停止饮酒后会出现酒精戒断。虽然酒精戒断通常是轻微的,但20%的患者会出现更严重的症状,如幻觉、癫痫发作和谵妄。在本研究中,我们利用全国住院患者样本来研究2010 - 2019年期间酒精戒断性谵妄(AWD)的趋势。方法:这是一项回顾性纵向趋势研究,涉及2010年至2019年美国因AWD住院的患者。我们使用国际疾病分类(ICD)代码(291.0和F10231)在数据库中检索住院病例。我们纳入了所有因AWD合并住院以及以AWD为主要入院诊断的住院情况。我们排除了18岁以下患者的住院情况。我们计算了每个日历年的粗入院率和每百万成人住院的AWD发生率。此外,我们还分析了住院死亡率、住院时间(LOS)和医院总收费(THC)的趋势。结果:每百万住院患者AWD发生率从2010年的2671.8例上升至2019年的3405.6例,年变化百分比(APC)为3.1% (P < 0.001)。同样,每百万住院患者的AWD住院率从2010年的1,030.3上升到2019年的1,556.0,平均APC为5.0% (P < 0.001)。在研究期间,住院病人死亡率、THC和LOS的增加趋势有统计学意义。一般来说,女性、年轻和黑人种族与更好的临床结果相关。结论:我们的研究显示AWD的发病率和住院率增加。死亡率、LOS和THC在研究期间有所增加。较年轻的年龄、女性和黑人种族与较好的临床结果相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Gastroenterology Research
Gastroenterology Research GASTROENTEROLOGY & HEPATOLOGY-
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