Imeglimin in type 2 diabetes.

IF 1.8 4区 医学 Q2 Medicine
Jessica Huston, Hannah Schaffner, Logan Langley, Blake Skrable, Andrea Ashchi, Jason Berner, Ashwini Gore, Mae Sheikh-Ali, David Sutton, Rebecca Goldfaden
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引用次数: 0

Abstract

Type 2 diabetes mellitus is a chronic disease most often characterized by increased glucose levels. When blood glucose levels are inadequately controlled or left untreated, the result is a variety of microvascular and macrovascular complications. To prevent these outcomes, many medications are available to manage type 2 diabetes mellitus and prevent disease progression. However, most of the medications available to date only target a few of the physiological defects caused by diabetes and may come with side effects that make adherence to the medication improbable. Imeglimin, a medication currently under investigation in the United States and approved in Japan, is a novel, first-in-its-class medication with a mechanism that is currently understood to target multiple pathways to provide glycemic control. This review aims to present and discuss the current clinical and scientific evidence pertaining to imeglimin.

2型糖尿病中的依米霉素。
2型糖尿病是一种慢性疾病,最常见的特征是血糖水平升高。当血糖水平控制不当或不及时治疗时,结果是各种微血管和大血管并发症。为了预防这些结果,许多药物可用于控制2型糖尿病和预防疾病进展。然而,到目前为止,大多数可用的药物只针对由糖尿病引起的几种生理缺陷,并且可能伴随副作用,使药物的坚持不太可能。imimimin是一种目前正在美国进行研究并在日本获得批准的药物,是一种新型的同类药物中的第一种,其机制目前被认为是针对多种途径提供血糖控制。这篇综述的目的是提出和讨论目前有关依米霉素的临床和科学证据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Drugs of today
Drugs of today 医学-药学
CiteScore
3.90
自引率
0.00%
发文量
48
审稿时长
6-12 weeks
期刊介绍: An international, peer-reviewed journal publishing monographs on new products entering the market and review articles. Since its inception in 1965, Drugs of Today has established a reputation for excellence in providing physicians and other key healthcare professionals with practical, up-to-date monographs on recently approved and launched drugs.
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