Effect of nutrition education on nutritional status and serum zinc level of HIV and AIDS clients: implication for care in resource-limited settings.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2022-10-01 Epub Date: 2022-09-14 DOI:10.2989/16085906.2022.2087532

Ifeyinwa Ezenwosu, Osita Ezenwosu, Chinyere Mbachu, Ijeoma Itanyi, Emmanuel Aguwa

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引用次数: 0

Abstract

Background: People living with HIV or AIDS in resource-limited settings are faced with challenges in their nutrition and micronutrient levels. This study aimed to determine the effect of nutrition education on the nutrition status and serum zinc level of HIV and AIDS clients, and its implication for HIV care in resource-limited settings.Methods: This intervention study was conducted among HIV clients at the University of Nigeria Teaching Hospital and Enugu State University Teaching Hospital, which served as the intervention and control groups respectively. A nutrition education programme was delivered to the intervention group. In both groups, before and after the intervention, the body mass index of participants was calculated using their height (m2) and weight (kg) while their serum zinc levels were analysed using spectrophotometry. Chi-square and McNemar chi-square tests were used in the analysis.Results: A total of 185 respondents was studied in each group, with the majority in the 30-39 and 40-49 age groups, respectively (65.4% of the study group and 64.4% of the control group). Larger proportions of respondents in both groups were females (72.4% vs 75.1% respectively). Three months after the intervention, the proportion of respondents with normal serum zinc levels improved significantly from 20.5% to 51.9% in the intervention group (χ²_McNemar, p < 0.001), whereas the control group had no appreciable improvement (16.8% vs 22.7%) (χ²_McNemar, p < 0.117). Furthermore, the post-intervention serum zinc level difference between the intervention and control groups was statistically significant (χ² = 33.699; p < 0.001). No statistically significant difference existed in the nutritional status between the groups (χ² = 3.469; p = 0.325).Conclusion: Nutrition education had a positive effect on the serum zinc levels of HIV clients. Integrating nutrition education programmes as a key component of HIV care in resource-limited settings will help improve the serum zinc level of people living with HIV, which ultimately improves their immune status and life expectancy.

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营养教育对HIV / AIDS患者营养状况和血清锌水平的影响:资源有限地区护理的意义

背景:在资源有限的环境中，艾滋病毒或艾滋病患者在营养和微量营养素水平方面面临挑战。本研究旨在探讨营养教育对HIV / AIDS患者营养状况和血清锌水平的影响，以及对资源有限地区HIV护理的启示。方法:对尼日利亚大学教学医院和埃努古州立大学教学医院的艾滋病患者进行干预研究，分别作为干预组和对照组。对干预组实施营养教育方案。在两组中，在干预前和干预后，使用身高(m2)和体重(kg)计算参与者的体重指数，同时使用分光光度法分析他们的血清锌水平。分析采用卡方检验和McNemar卡方检验。结果:每组共185名调查对象，其中30-39岁和40-49岁年龄组占多数(研究组占65.4%，对照组占64.4%)。两组受访者中女性的比例都较大(分别为72.4%和75.1%)。干预3个月后，干预组患者血清锌水平正常的比例由20.5%显著提高至51.9% (χ2McNemar, p < 0.001)，而对照组无明显改善(16.8% vs 22.7%) (χ2McNemar, p < 0.117)。干预后血清锌水平与对照组比较差异有统计学意义(χ2 = 33.699;P < 0.001)。两组间营养状况差异无统计学意义(χ2 = 3.469;P = 0.325)。结论:营养教育对HIV感染者血清锌水平有积极影响。在资源有限的环境中，将营养教育规划作为艾滋病毒护理的一个关键组成部分，将有助于改善艾滋病毒感染者的血清锌水平，从而最终改善他们的免疫状况和预期寿命。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.