Heart Failure Status among Acute Ischemic Stroke Patients: A Hospital-Based Study.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2022-08-24 eCollection Date: 2022-01-01 DOI:10.1155/2022/7348505

Fatemeh Ravandi, Arsh Haj Mohamad Ebrahim Ketabforoush, Fereshteh Azedi, Mohsen Hoshyarkhani, Farimah Fayyaz, Nahid Abbasi Khoshsirat

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引用次数: 3

Abstract

Background: Since heart failure (HF) and ischemic stroke have common risk factors, their concurrent occurrence is likely. Strokes in HF patients could be life-threatening and lead to severe disabilities, longer hospitalization time, and mortality. The present study aims to investigate the prevalence of HF and its severity based on ejection fraction (EF) in patients with acute ischemic stroke.

Methods: The present cross-sectional study included acute ischemic stroke patients admitted to Shahid Rajaei hospital in Karaj in 2020-2021. The diagnosis of HF was based on transthoracic echocardiography within 48 hours of symptom onset, and HF was classified into two groups: 41-49% as mildly reduced EF (HFmrEF) and ≤40% as reduced EF (HFrEF). Patients who did not complete cardiac studies were excluded.

Results: 257 acute ischemic stroke patients (62.6% male) were included. Among stroke patients, the prevalence of HF, including HFrEF and HFmrEF, was 30.0% (95% CI: 21.4-38.6). HFmrEF and HFrEF was diagnosed in 32 (12.5%) and 45 (17.5%) patients, respectively. HF was significantly associated with older age, hypertension, past myocardial infarction (MI), and arrhythmia. A history of previous MI significantly increased the odds of heart failure (OR: 3.25, 95% CI: 1.82-5.81).

Conclusion: There is a high prevalence of HF among acute ischemic stroke patients. Older patients with a history of hypertension and previous MI are at higher risk. Since patients with HF have a higher mortality and morbidity rate after experiencing an ischemic stroke, close cooperation between the neurology and cardiology specialists for providing advanced care for survivors is required.

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急性缺血性脑卒中患者心衰状况:一项基于医院的研究

背景:由于心力衰竭(HF)和缺血性脑卒中具有共同的危险因素，它们很可能同时发生。心衰患者的中风可能危及生命，导致严重残疾、住院时间延长和死亡。本研究旨在探讨急性缺血性脑卒中患者中基于射血分数(EF)的HF患病率及其严重程度。方法:本横断面研究纳入2020-2021年在卡拉伊Shahid Rajaei医院住院的急性缺血性脑卒中患者。HF的诊断基于症状出现48小时内的经胸超声心动图，并将HF分为两组:41-49%为EF轻度降低(HFmrEF)，≤40%为EF降低(HFrEF)。未完成心脏研究的患者被排除在外。结果:纳入急性缺血性脑卒中257例，男性62.6%。在脑卒中患者中，HF(包括HFrEF和HFmrEF)的患病率为30.0% (95% CI: 21.4-38.6)。确诊HFmrEF和HFrEF的患者分别为32例(12.5%)和45例(17.5%)。HF与老年、高血压、既往心肌梗死(MI)和心律失常显著相关。既往心肌梗死史显著增加心力衰竭的几率(OR: 3.25, 95% CI: 1.82-5.81)。结论:急性缺血性脑卒中患者心衰发生率较高。有高血压病史和心肌梗死史的老年患者发生心肌梗死的风险更高。由于心衰患者在经历缺血性卒中后具有较高的死亡率和发病率，因此需要神经病学和心脏病学专家之间的密切合作，为幸存者提供高级护理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.