The New Distance-Based Kidney Allocation System: Implications for Patients, Transplant Centers, and Organ Procurement Organizations.

IF 1.5 Q2 SURGERY
Current Transplantation Reports Pub Date : 2022-01-01 Epub Date: 2022-10-13 DOI:10.1007/s40472-022-00384-z
David C Cron, Syed A Husain, Joel T Adler
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引用次数: 6

Abstract

Purpose of review: The goal of deceased donor kidney allocation policy is to provide objective prioritization for donated kidneys, and policy has undergone a series of revisions in the past decade in attempt to achieve equity and utility in access to kidney transplantation. Most recently, to address geographic disparities in access to kidney transplantation, the Kidney Allocation System changed to a distance-based allocation system-colloquially termed "KAS 250"-moving away from donor service areas as the geographic basis of allocation. We review the early impact of this policy change on access to transplant for patients, and on complexity of organ allocation and transplantation for transplant centers and organ procurement organizations.

Recent findings: Broader sharing of kidneys has increased complexity of the allocation system, as transplant centers and OPOs now interact in larger networks. The increased competition resulting from this system, and the increased operational burden on centers and OPOs resulting from greater numbers of organ offers, may adversely affect organ utilization. Preliminary results suggest an increase in transplant rate overall but a trend toward higher kidney discard and increased cold ischemia time.

Summary: The KAS 250 allocation policy changed the geographic basis of deceased donor kidney distribution in a manner that is intended to reduce geographic disparities in access to kidney transplantation. Close monitoring of this policy's impact on patients, transplant center behavior, and process measures is critical to the aim of maximizing access to transplant while achieving transplant equity.

Abstract Image

新的基于距离的肾脏分配系统:对患者、移植中心和器官采购组织的影响。
回顾目的:已故供者肾脏分配政策的目标是为捐赠的肾脏提供客观的优先级,在过去的十年中,政策经历了一系列的修订,试图实现肾脏移植的公平和效用。最近,为了解决在获得肾移植方面的地理差异,肾脏分配系统改为基于距离的分配系统,通俗地称为“KAS 250”,不再以供体服务区作为分配的地理基础。我们回顾了这一政策变化对患者获得移植的早期影响,以及对移植中心和器官采购组织器官分配和移植的复杂性的影响。最近的研究发现:肾脏的广泛共享增加了分配系统的复杂性,因为移植中心和opo现在在更大的网络中相互作用。该系统导致的竞争加剧,以及器官供应数量增加导致中心和opo的运营负担增加,可能会对器官的利用产生不利影响。初步结果表明,移植率总体上增加,但有更高的肾脏丢弃和增加冷缺血时间的趋势。摘要:KAS 250分配政策改变了已故供体肾脏分配的地理基础,旨在减少获得肾移植的地理差异。密切监测这一政策对患者、移植中心行为和过程措施的影响,对于在实现移植公平的同时最大限度地获得移植机会至关重要。
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来源期刊
CiteScore
3.40
自引率
4.80%
发文量
34
期刊介绍: Under the guidance of Dr. Dorry Segev, from Johns Hopkins, Current Transplantation Reports will provide an in-depth review of topics covering kidney, liver, and pancreatic transplantation in addition to immunology and composite allografts.We accomplish this aim by inviting international authorities to contribute review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists.  By providing clear, insightful balanced contributions, the journal intends to serve those involved in the field of transplantation.
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