Amanda P Ahrens Kress, Yudi Zhang, Adrianne R Kaiser-Vry, Mary B Sauer
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引用次数: 3
Abstract
Multiple methods are used to collect blood from mice; these methods have different effects on animal welfare. This study compared blood collection from facial, chin, and saphenous locations with regard to various parameters, including the time needed to collect blood, the number of attempts needed, success at completing the blood collection, volume of blood loss, weight changes in the mouse, presence of external lesions after blood collection and gross lesions at necropsy, physical signs during blood collection (vocalization, urination, and defecation), fecal corticosterone after blood collection, and blood chemistry values. While no one technique was clearly better for animal welfare, each technique had benefits and drawbacks.
期刊介绍：
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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