Topographic assessment of retinal pigment epithelium detachment in central serous chorioretinopathy by three-dimensional optical coherence tomography single-layer retinal pigment epithelium map.

Journal of ocular biology, diseases, and informatics Pub Date : 2013-01-31 eCollection Date: 2012-06-01 DOI:10.1007/s12177-013-9099-0

Sandeep Saxena, Carsten H Meyer, Shashi R Sharma

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Abstract

Purpose: This study aims to compare the topographic distribution of retinal pigment epithelium detachment (PED) in central serous chorioretinopathy (CSC) on spectral domain optical coherence tomography (SD-OCT) single-layer retinal pigment epithelium (SL-RPE) map and fluorescein angiography for the first time.

Methods: Twenty-seven eyes of CSC with PEDs were studied retrospectively. Topographic distribution of PEDs was documented on 50° fluorescein angiography and SD-OCT SL-RPE map on macular cube 512 × 128.

Results: Quantity of PEDs ranged from 1 to 5 on SD-OCT SL-RPE map macular cube 512 × 128 and corresponding macular cube area on 50° fluorescein angiography. Topographic distribution of PEDs on SL-RPE map matched with PEDs on fluorescein angiography in the corresponding macular cube area, in all the cases (interobserver correlation = 0.9).

Conclusion: SD-OCT SL-RPE map is a noninvasive, three-dimensional advanced tool for documentation of topographic assessment of PEDs and obviates the need of fluorescein angiography for monitoring CSC.

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三维光学相干断层扫描单层视网膜色素上皮图对中枢性浆液性脉络膜视网膜病变视网膜色素上皮脱离的地形学评价。

目的:首次比较中央性浆液性脉络膜视网膜病变(CSC)视网膜色素上皮脱离(PED)在光谱域光学相干断层扫描(SD-OCT)单层视网膜色素上皮(SL-RPE)图和荧光素血管造影上的地形分布。方法:对27只CSC合并PEDs的眼进行回顾性研究。采用50°荧光素血管造影和512 × 128黄斑立方SD-OCT SL-RPE图记录PEDs的地形分布。结果:SD-OCT SL-RPE图512 × 128黄斑立方及50°荧光素血管造影对应黄斑立方区域，ped数量为1 ~ 5个。在所有病例中，SL-RPE图上PEDs的地形分布与荧光素血管造影显示的相应黄斑立方区域PEDs相匹配(观察者间相关性= 0.9)。结论:SD-OCT SL-RPE图是一种无创、三维的先进工具，可用于记录PEDs的地形评估，无需荧光素血管造影监测CSC。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Journal of ocular biology, diseases, and informatics

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