Epidemiology of Diabetes Foot Amputation and its Risk Factors in the Middle East Region: A Systematic Review and Meta-Analysis.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2025-03-01 Epub Date: 2022-06-21 DOI:10.1177/15347346221109057

Fatemeh Bandarian, Mostafa Qorbani, Ensieh Nasli-Esfahani, Mahnaz Sanjari, Camelia Rambod, Bagher Larijani

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引用次数: 0

Abstract

This study aimed to review epidemiology of diabetic foot (DF) amputation and provide a pooled estimation of DF amputation rate in the region. A comprehensive search was performed in Web of Science, PubMed, Scopus and EMBASE databases using appropriate search term. Obtained records were entered endnote software and after removing duplicats were screened by title, abstract and full text. Data was extracted from the remained documents. Random effect meta-analysis was used to pool the estimated prevalence rate due to sever heterogeneity between studies. Finally 17 articles in diabetes, 20 in patients with DFU (diabetic foot ulcer) and two in both remained after screening and included in meta-analysis. Overall pooled amputation rate in diabetes was 2% (95% CI: 1%-3%) which was not significantly different between countries. The pooled prevalence of amputation rate in DFU patients was 33% (24%-43%) and the pooled prevalence in Saudi Arabia was significantly higher than in other countries. The estimated rate of foot amputation in diabetes patients and those with DFUs in the Middle East region is approximately high, which may indicate low quality of preventive foot care, low socioeconomics and low patients awareness or education in countries with high amputation rate.

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中东地区糖尿病足截肢的流行病学及其风险因素：系统回顾与元分析》。

本研究旨在回顾糖尿病足截肢的流行病学，并对该地区糖尿病足截肢率进行汇总估算。研究人员使用适当的检索词在 Web of Science、PubMed、Scopus 和 EMBASE 数据库中进行了全面检索。获得的记录输入 endnote 软件，去除重复内容后，通过标题、摘要和全文进行筛选。从保留的文献中提取数据。由于各研究之间存在严重的异质性，因此采用随机效应荟萃分析法对估计的患病率进行汇总。经过筛选，最终有 17 篇关于糖尿病的文章、20 篇关于 DFU（糖尿病足溃疡）患者的文章和 2 篇关于两者的文章被纳入荟萃分析。糖尿病患者的总截肢率为 2%（95% CI：1%-3%），各国之间差异不大。DFU患者的总截肢率为33%（24%-43%），沙特阿拉伯的总截肢率明显高于其他国家。据估计，中东地区糖尿病患者和DFU患者的足部截肢率大约很高，这可能表明在截肢率较高的国家中，预防性足部护理的质量较低、社会经济水平较低以及患者的意识或教育水平较低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.