Comparative Evaluation of Clinical Efficacy of Leukocyte-Rich Platelet-Rich Fibrin with Advanced Platelet-Rich Fibrin in Management of Gingival Recession Defects: A Randomized Controlled Trial.

Anupama Tadepalli, Swapna Chekurthi, Swarupa Kavassery Balasubramanian, Harinath Parthasarathy, Deepa Ponnaiyan
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引用次数: 1

Abstract

Background: The aim of this research was to determine and compare the clinical efficacy of leukocyte platelet-rich fibrin (L-PRF) and advanced platelet-rich fibrin (A-PRF) in combination with coronally advanced flap (CAF) in the treatment of gingival recession defects.

Methods: Systemically healthy subjects presenting with 30 Miller's class I or II gingival recession defects in maxillary anteriors and premolars, were treated with either CAF + L-PRF or CAF + A-PRF. Clinical parameters such as recession height (RH), width, probing pocket depth, clinical attachment level (CAL), keratinized tissue height (KTH), and width of attached gingiva (WAG) were measured at baseline, 3, and 6 months. Gingival biotype was evaluated at baseline and 6 months post-surgery. Mean root coverage percentage (MRC%) was evaluated at 3 and 6 months.

Results: Statistically significant reduction in mean RH was observed from baseline (2.53 ± 0.74 mm, 2.63 ± 0.82 mm) to 6 months (0.87 ± 0.83 mm, 0.53 ± 0.91 mm) in CAF + L-PRF and CAF + A-PRF groups, respectively. The MRC% achieved at 6 months was 67.20 ± 32.81 in the CAF + L-PRF group and 81.66 ± 28.21 in the CAF + A-PRF group. Statistically significant gain in CAL, WAG, and KTH was observed in both therapeutic groups (p < 0.05). Intergroup analysis revealed no statistically significant differences among study parameters between groups at any time point (p > 0.05).

Conclusion: Based on the findings of this study, both L-PRF and A-PRF may be suggested as viable treatment options for the management of gingival recession in maxilla.

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富白细胞富血小板纤维蛋白与晚期富血小板纤维蛋白治疗牙龈退行性缺损的临床疗效比较:一项随机对照试验。
背景:本研究的目的是确定和比较白细胞富血小板纤维蛋白(L-PRF)和晚期富血小板纤维蛋白(A-PRF)联合冠状晚期皮瓣(CAF)治疗牙龈退缩缺损的临床疗效。方法:采用CAF + L-PRF或CAF + A-PRF治疗上颌前牙和前磨牙牙龈退缩缺损30例。在基线、3个月和6个月测量临床参数,如消退高度(RH)、宽度、探测袋深度、临床附着水平(CAL)、角化组织高度(KTH)和附着龈宽度(WAG)。在基线和术后6个月评估牙龈生物型。在3个月和6个月时评估平均根覆盖度。结果:CAF + L-PRF组和CAF + A-PRF组从基线(2.53±0.74 mm, 2.63±0.82 mm)到6个月(0.87±0.83 mm, 0.53±0.91 mm)的平均RH降低具有统计学意义。6个月时,CAF + L-PRF组的MRC%为67.20±32.81,CAF + A-PRF组为81.66±28.21。两组患者CAL、WAG、KTH升高均有统计学意义(p < 0.05)。组间分析显示,各时间点组间研究参数差异无统计学意义(p > 0.05)。结论:基于本研究结果,L-PRF和A-PRF均可作为治疗上颌骨牙龈萎缩的可行治疗方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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