THE EFFECT OF PROSTIGMIN ON THE URINARY EXCRETION OF POTASSIUM IN THE NORMAL SUBJECT.

Abstract

From the Biochemical Department, National Hospital, Queen Square, London PREVIOUS work (Cumings, 1940) on the effect of prostigmin (mgm. i) in patients suffering from myasthenia gravis showed that although potassium was liberated from affected muscles and circulated in the blood, the urine did not show any increased amount of potassium. It was assumed that prostigmin did not in any way cause this retention of potassium in that it had no effect on the kidney, and upon this assumption certain deductions were made. The present paper describes an attempt to show that this assumption was correct.