Niloy Bhadra, Tina L Vrabec, Narendra Bhadra, Kevin L Kilgore
{"title":"Reversible conduction block in peripheral nerve using electrical waveforms.","authors":"Niloy Bhadra, Tina L Vrabec, Narendra Bhadra, Kevin L Kilgore","doi":"10.2217/bem-2017-0004","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Electrical nerve block uses electrical waveforms to block action potential propagation.</p><p><strong>Materials & methods: </strong>Two key features that distinguish electrical nerve block from other nonelectrical means of nerve block: block occurs instantly, typically within 1 s; and block is fully and rapidly reversible (within seconds).</p><p><strong>Results: </strong>Approaches for achieving electrical nerve block are reviewed, including kilohertz frequency alternating current and charge-balanced polarizing current. We conclude with a discussion of the future directions of electrical nerve block.</p><p><strong>Conclusion: </strong>Electrical nerve block is an emerging technique that has many significant advantages over other methods of nerve block. This field is still in its infancy, but a significant expansion in the clinical application of this technique is expected in the coming years.</p>","PeriodicalId":72364,"journal":{"name":"Bioelectronics in medicine","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811084/pdf/bem-01-39.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioelectronics in medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2217/bem-2017-0004","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2017/12/14 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
Materials & methods: Two key features that distinguish electrical nerve block from other nonelectrical means of nerve block: block occurs instantly, typically within 1 s; and block is fully and rapidly reversible (within seconds).
Results: Approaches for achieving electrical nerve block are reviewed, including kilohertz frequency alternating current and charge-balanced polarizing current. We conclude with a discussion of the future directions of electrical nerve block.
Conclusion: Electrical nerve block is an emerging technique that has many significant advantages over other methods of nerve block. This field is still in its infancy, but a significant expansion in the clinical application of this technique is expected in the coming years.