Acute Response to One Bout of Dynamic Standing Exercise on Blood Glucose and Blood Lactate Among Children and Adolescents With Cerebral Palsy Who are Nonambulant.

IF 1.4 4区医学 Q3 PEDIATRICS

Pediatric Exercise Science Pub Date : 2022-05-01 Epub Date: 2022-01-10 DOI:10.1123/pes.2021-0098

Petra Lundström, Katarina Lauruschkus, Åsa Andersson, Åsa B Tornberg

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引用次数: 1

Abstract

Purpose: To investigate the acute exercise effects of dynamic standing exercise on blood glucose and blood lactate among children and adolescents with cerebral palsy who are nonambulant.

Methods: Twenty-four participants with cerebral palsy who are nonambulant performed 30 minutes of dynamic standing exercise using a motorized device enabling assisted passive movements in an upright weight-bearing position. Capillary blood samples were taken from the fingertip for measurement of blood glucose and blood lactate at rest and at the end of exercise.

Results: At rest, the participants had hyperlactatemia that was unaffected after exercise, presented as median and interquartile range at rest 1.8 (1.3:2.7) mmol/L, and after exercise 2.0 (1.1:2.5) mmol/L. Children and adolescents with Gross Motor Function Classification System, level V, had higher lactate levels at rest (2.5 [1.8:2.9] vs 1.4 [1.0:2.0]; P = .030) and after exercise (2.3 [2.0:2.6] vs 1.2 [0.9:2.2]; P = .032) compared with children and adolescents with Gross Motor Function Classification System, level IV, respectively. A statistically significant larger decrease in blood lactate levels after exercise was observed in children and adolescents with higher resting blood lactate levels (ρ = .56; P = .004). There were no statistically significant changes in blood glucose.

Conclusions: Forty percentage of the participants had mild hyperlactatemia at rest and participants with the highest blood lactate levels at rest had the greatest decrease in blood lactate levels after one bout of exercise. Children and adolescents who were classified with the highest level of the Gross Motor Function Classification Scale had higher blood lactate levels. More studies are needed on how to prevent chronically high resting levels of lactate with exercise in children with cerebral palsy who are nonambulant.

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一次动态站立运动对不能走动的脑瘫儿童和青少年血糖和血乳酸的急性反应。

目的:探讨动态站立运动对不能走动的脑瘫儿童和青少年血糖和血乳酸的急性运动影响。方法:24名不能走动的脑瘫患者使用一种能在直立负重位置辅助被动运动的机动装置进行30分钟的动态站立锻炼。在休息和运动结束时，从指尖采集毛细血管血样，测量血糖和血乳酸。结果:在休息时，参与者有高乳酸血症，运动后不受影响，休息时为1.8 (1.3:2.7)mmol/L，运动后为2.0 (1.1:2.5)mmol/L。大运动功能分类系统为V级的儿童和青少年在休息时乳酸水平较高(2.5 [1.8:2.9]vs 1.4 [1.0:2.0]);P = 0.030)和运动后(2.3 [2.0:2.6]vs 1.2 [0.9:2.2]);P = 0.032)，分别与大运动功能分类系统IV级儿童和青少年进行比较。在静息血乳酸水平较高的儿童和青少年中，运动后血乳酸水平的下降有统计学意义(ρ = 0.56;P = .004)。血糖没有统计学上的显著变化。结论:40%的参与者在休息时患有轻度高乳酸血症，而休息时血乳酸水平最高的参与者在一次运动后血乳酸水平下降幅度最大。大运动功能分级量表最高的儿童和青少年血乳酸水平较高。如何通过运动预防不能活动的脑瘫儿童的长期高静息乳酸水平需要更多的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pediatric Exercise Science 医学-生理学

CiteScore

2.80

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Pediatric Exercise Science is a journal committed to enriching the scientific knowledge of exercise during childhood and adolescence. To this end it publishes information that contributes to an understanding of (a) the unique aspects of the physiologic, physical, biochemical, and psychologic responses of children to exercise, (b) the role of exercise in the treatment of pediatric chronic diseases, (c) the importance of physical activity in the prevention of illness and preservation of wellness, and (d) the means by which participation in sports may be made safer and more enjoyable for children and youth. Consideration will be given for publication of work by various methodologies consistent with the scientific approach. Besides original research, the journal includes review articles, abstracts from other journals, book reviews, and editorial comments. Pediatric Exercise Science encourages the expression of conflicting opinions regarding children and exercise by providing a forum for alternative viewpoints. At the same time it serves as a means of accumulating a base of research information that will allow application of experimental data to clinical practice. The scientific disciplines contributing to this body of knowledge are diverse. Therefore it is the purpose of this journal to provide a common focus for disseminating advances in the science of exercise during childhood. In doing so, the journal allows the opportunity for cross-fertilization of ideas between disciplines that will potentiate the growth of knowledge in this field. Pediatric Exercise Science seeks to stimulate new ideas regarding exercise in children and to increase the awareness of scientists, health care providers, and physical educators of the importance of exercise during childhood.