Assessment of semen parameters in consecutive ejaculates with short abstinence period in oligospermic males.

IF 1.9
Vinuta Kulkarni, Pankaj Kaingade, Namrata Kulkarni, Tejal Bhalerao, Amar Nikam
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引用次数: 5

Abstract

Objective: Human sperm parameters varies widely among men and even between consecutive samples in the same individual with respect to their concentration, motility, morphology, and DNA fragmentation. Less is known about the characteristics of sperm in short abstinence periods. Hence, the current study was conducted to determine the influence of consecutive ejaculate on above parameters after short abstinence period in oligospermic males.

Methods: This observational study was conducted from January 2018 to February 2019 and included 67 men undergoing primary infertility treatment at the SDM Fertility Centre, Dharwad, India. The first semen sample was provided after an abstinence period of 2-7 days, while the second sample was collected 1-3 h after the first. The two consecutive semen samples were analyzed according to the 2010 WHO criteria for semen analysis and their parameters were compared. Sperm DNA fragmentation was also measured.

Results: Most of the participants were aged of 31 to 40 years (68.6%). The majority of them had the second sample collected after a 1-hour interval (88%); 10.4% of the subjects had the second sample collected after a 2-hour interval; the remaining 1.4% had the second sample collected after a 3-hour interval. Mean concentration (mill/ml), total motility, and progressive motility (%) were significantly higher in the second sample (p<0.05). The second sample also showed lower DNA fragmentation than the first ejaculate sample.

Conclusions: Our study inferred that consecutive semen samples collected 1-3 hours apart might have a role in managing subfertility in oligospermic males. Further research, possibly a randomized clinical trial, is needed to explore this association.

Abstract Image

少精子男性短节育期连续射精的精液参数评价。
目的:人类精子参数在男性之间,甚至在同一个体的连续样本之间,就其浓度、运动性、形态和DNA片段而言,差异很大。人们对短时间禁欲期间精子的特征知之甚少。因此,本研究旨在确定少精子男性在短时间禁欲后连续射精对上述参数的影响。方法:这项观察性研究于2018年1月至2019年2月进行,包括67名在印度达瓦德SDM生育中心接受原发性不孕症治疗的男性。第一份精液在禁欲2-7天后采集,第二份精液在禁欲1-3小时后采集。按照2010年世界卫生组织精液分析标准对连续两份精液样本进行分析,并对其各项参数进行比较。精子DNA断裂也被测量。结果:年龄以31 ~ 40岁居多(68.6%)。其中大多数在间隔1小时后采集第二次样本(88%);10.4%的受试者每隔2小时采集第二次样本;剩下的1.4%每隔3小时采集第二次样本。在第二个样本中,平均浓度(ml /ml)、总活力和进展活力(%)显著更高(结论:我们的研究推断,间隔1-3小时收集的连续精液样本可能对控制少精子男性的低生育能力有作用。进一步的研究,可能是随机临床试验,需要探索这种联系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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