Comprehensive evaluation of left ventricular deformation using speckle tracking echocardiography in normal children: comparison of three-dimensional and two-dimensional approaches.

IF 1.9 3区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Cardiovascular Ultrasound Pub Date : 2022-01-27 DOI:10.1186/s12947-022-00273-6

Doaa Aly, Nitin Madan, Laura Kuzava, Alison Samrany, Anitha Parthiban

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引用次数: 0

Abstract

Background: Three-dimensional (3D) speckle tracking echocardiography (STE) can overcome some of the inherent limitations of two-dimensional (2D) STE; however, clinical experience is lacking. We aimed to assess and compare the feasibility, agreement, and reproducibility of left ventricular (LV) global longitudinal (GLS), and regional strain by 3D vs 2D STE in normal children.

Methods: Healthy pediatric subjects (n = 105, age mean = 11.2 ± 5.5 years) were prospectively enrolled. Three-dimensional and 2D LV GLS, as well as regional strain in 16 myocardial segments were quantified. Bland Altman analysis, intra- class correlation coefficients (ICC), percent error and linear regression were used for agreement and correlation between the two techniques. Analysis and acquisition times were compared. Inter- and intra-observer reproducibility was assessed in 20 studies.

Results: There was good to excellent agreement for 2D and 3D global longitudinal strain (ICC =0.82) and modest agreement for regional strain (ICC range 0.43-0.71). Both methods had high feasibility (88.6% for 2D vs 85.7% for 3D, p = 0.21), although 3D STE required significantly shorter acquisition and analysis time than 2D STE (acquisition time 1 ± 1.2 mins vs 2.4 ± 1 mins; p = 0.03, analysis time = 3.3 ± 1 mins vs 8.2 ± 2.5 mins; p = 0.001, respectively). Inter and intra-observer reproducibility was excellent for GLS by the two techniques (ICC = 0.78-0.93) but moderate to poor for regional strain (ICC = 0.21-0.64).

Conclusion: Three-dimensional global LV strain is as feasible and reproducible as 2D strain, with good agreement yet significantly more efficient acquisition and analysis. Regional strain is less concordant and 2D and 3D values should not be used interchangeably. 3D LV GLS may represent a viable alternative in evaluation of LV deformation in pediatric subjects.

查看原文本刊更多论文

斑点跟踪超声心动图对正常儿童左心室变形的综合评价:三维和二维方法的比较。

背景:三维(3D)斑点跟踪超声心动图(STE)可以克服二维(2D) STE的一些固有局限性;但临床经验不足。我们的目的是评估和比较正常儿童左心室(LV)整体纵向(GLS)和局部应变的3D和2D STE的可行性、一致性和可重复性。方法:前瞻性纳入健康儿童受试者105例，平均年龄为11.2±5.5岁。定量左室三维、二维GLS及16个心肌节段的局部应变。采用Bland Altman分析、类内相关系数(inter - class correlation coefficients, ICC)、误差百分比和线性回归分析两种方法的一致性和相关性。分析时间和采集时间进行了比较。在20项研究中评估了观察者之间和观察者内部的可重复性。结果:二维和三维整体纵向应变具有较好的一致性(ICC =0.82)，区域应变具有较好的一致性(ICC范围为0.43-0.71)。两种方法的可行性都很高(2D为88.6%，3D为85.7%，p = 0.21)，尽管3D STE所需的采集和分析时间明显短于2D STE(采集时间1±1.2分钟vs 2.4±1分钟;p = 0.03,分析时间= 3.3±1分钟和8.2±2.5分钟;P = 0.001)。两种方法对GLS的重现性在观察者间和观察者内均较好(ICC = 0.78 ~ 0.93)，但对区域菌株的重现性较差(ICC = 0.21 ~ 0.64)。结论:三维全局LV菌株与二维菌株具有相同的可行性和可重复性，一致性好，采集和分析效率显著提高。区域应变不太协调，2D和3D值不应互换使用。三维左室GLS可能代表一个可行的替代评估左室变形在儿科受试者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cardiovascular Ultrasound CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

4.10

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Cardiovascular Ultrasound is an online journal, publishing peer-reviewed: original research; authoritative reviews; case reports on challenging and/or unusual diagnostic aspects; and expert opinions on new techniques and technologies. We are particularly interested in articles that include relevant images or video files, which provide an additional dimension to published articles and enhance understanding. As an open access journal, Cardiovascular Ultrasound ensures high visibility for authors in addition to providing an up-to-date and freely available resource for the community. The journal welcomes discussion, and provides a forum for publishing opinion and debate ranging from biology to engineering to clinical echocardiography, with both speed and versatility.