Olmesartán y enteropatía una década después: una asociación quizá no tan excepcional

Abstract

Olmesartan is a potent angiotensin II receptor antagonist commonly used in the treatment of high blood pressure.

During the last decade, several cases of sprue-like enteropathy have been described associated with the use of this drug - with severe clinical involvement that requires hospitalization - but fortunately with complete remission after its discontinuation.

We present the case of a multi-pathological 82-year-old woman with a chronic diarrhoeal syndrome that resulted in a weight loss of 20 kg over the last three months. She was prescribed dual therapy for her hypertension: olmesartan 40 mg, torasemide 10 mg, and lercanidipine 10 mg/day.

Based on the findings of the patient presented, we conducted a literature search of all the cases published in Spanish indexed journals (PubMed) and compared them, attempting to establish a suspicion profile that would result in the suspension of olmesartan and accelerate the complementary tests necessary to rule out other diagnoses.