Placement accuracy of the second electrode in bilateral deep brain stimulation surgery.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-10-01 Epub Date: 2021-12-23 DOI:10.1080/02688697.2021.2019677

Krishnapundha Bunyaratavej, Onanong Phokaewvarangkul, Piyanat Wangsawatwong

{"title":"Placement accuracy of the second electrode in bilateral deep brain stimulation surgery.","authors":"Krishnapundha Bunyaratavej, Onanong Phokaewvarangkul, Piyanat Wangsawatwong","doi":"10.1080/02688697.2021.2019677","DOIUrl":null,"url":null,"abstract":"Purpose: Due to brain shift during bilateral deep brain stimulation (DBS) surgery, placement of the second electrode may be subjected to more error than that of the first electrode. The authors aimed to investigate the accuracy of second electrode placement in this setting.Materials and methods: Fifty-five patients with Parkinson's disease who underwent bilateral DBS surgery (110 electrodes) were retrospectively evaluated. The targets were subthalamic nucleus (STN) and globus pallidus interna (GPi) in 40 and 15 cases, respectively. Preoperative planning and postoperative electrode images were co-registered to compare the error margin between the two sides.Results: There is a statistically significant difference in the directional axis error along the y axis only when comparing each laterality (posterior 0.04 ± 1.21 mm vs anterior 0.41 ± 1.07 mm, p = 0.006). There is no significant difference of other error parameters, final track location, and number of microelectrode recording passes between the two sides. In a subgroup analysis, there is a significant difference in directional axis error along the y axis only in the STN subgroup (posterior 0.40 ± 1.05 mm vs anterior 0.18 ± 1.04 mm, p = 0.003).Conclusion: Although a statistically significant difference in directional axis error along the y axis was found between first and second electrode placements in the STN group but not in the GPi group, its magnitude is well below the clinically significant threshold.","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/02688697.2021.2019677","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/12/23 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose: Due to brain shift during bilateral deep brain stimulation (DBS) surgery, placement of the second electrode may be subjected to more error than that of the first electrode. The authors aimed to investigate the accuracy of second electrode placement in this setting.

Materials and methods: Fifty-five patients with Parkinson's disease who underwent bilateral DBS surgery (110 electrodes) were retrospectively evaluated. The targets were subthalamic nucleus (STN) and globus pallidus interna (GPi) in 40 and 15 cases, respectively. Preoperative planning and postoperative electrode images were co-registered to compare the error margin between the two sides.

Results: There is a statistically significant difference in the directional axis error along the y axis only when comparing each laterality (posterior 0.04 ± 1.21 mm vs anterior 0.41 ± 1.07 mm, p = 0.006). There is no significant difference of other error parameters, final track location, and number of microelectrode recording passes between the two sides. In a subgroup analysis, there is a significant difference in directional axis error along the y axis only in the STN subgroup (posterior 0.40 ± 1.05 mm vs anterior 0.18 ± 1.04 mm, p = 0.003).

Conclusion: Although a statistically significant difference in directional axis error along the y axis was found between first and second electrode placements in the STN group but not in the GPi group, its magnitude is well below the clinically significant threshold.

查看原文本刊更多论文

双侧脑深部刺激手术中第二电极的放置准确性。

目的：在双侧脑深部刺激（DBS）手术中，由于脑部偏移，第二电极的放置可能比第一电极的放置误差更大。作者旨在研究在这种情况下第二电极放置的准确性：对 55 名接受双侧 DBS 手术（110 个电极）的帕金森病患者进行了回顾性评估。分别有 40 例和 15 例患者接受了眼下核（STN）和苍白球间质（GPi）手术。对术前计划和术后电极图像进行了联合注册，以比较双方的误差范围：结果：两侧比较，只有 y 轴方向的轴误差有显著统计学差异（后 0.04 ± 1.21 mm vs 前 0.41 ± 1.07 mm，p = 0.006）。两侧的其他误差参数、最终轨迹位置和微电极记录次数均无明显差异。在亚组分析中，只有 STN 亚组沿 y 轴的方向轴误差存在显著差异（后 0.40 ± 1.05 mm vs 前 0.18 ± 1.04 mm，p = 0.003）：尽管在 STN 组发现第一和第二电极放置之间沿 y 轴的方向轴误差存在统计学意义上的显著差异，而在 GPi 组则没有发现这种差异，但其幅度远低于具有临床意义的阈值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.