Il-Su Kwon, Deuk-Su Park, Hyeon-Cheol Shin, Myung-Gyu Seok, Jae-Keun Oh
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引用次数: 0
Abstract
Purpose: We aimed to identify the effects of marine oligomeric polyphenol (MOP) intake in elderly individuals with sarcopenia.
Methods: Older adults (aged 65 years or older) were recruited based on the diagnostic criterion for sarcopenia and were randomly assigned to the MOP intake group (n=10) or the placebo (PBO) intake group (n=10). To determine the effect of MOP intake received for four weeks, the pre- and post-intake body composition (weight, skeletal muscle mass, and bone density) and senior fitness tests were assessed.
Results: Our results showed there were significant differences in the skeletal muscle mass (p=0.039), bone density (p=0.020), fat-free mass index (p=0.026), and 2.4 m up and go test (p=0.001) between pretest and post-test. There was a significant difference between the pre-test and post-test and an interaction effect for the one-leg stand test (p=0.010 and p=0.049, respectively). However, there were no significant differences in body fat percentage, calf circumference, grip strength, or the chair rise test.
Conclusion: Some variables exhibited significant differences in the pre- and post-assessments, and there was an interaction effect for the one-leg stand. However, this was insufficient to prove the effectiveness of MOP intake in improving sarcopenia. Therefore, additional studies are essential to examine the effects of MOP intake and exercise intervention on the body composition and fitness of patients over a longer period.
目的:我们旨在确定海洋低聚多酚(MOP)摄入对老年肌肉减少症患者的影响。方法:根据肌肉减少症的诊断标准招募年龄在65岁及以上的老年人,随机分为MOP摄入组(n=10)和安慰剂(PBO)摄入组(n=10)。为了确定连续四周摄入MOP的效果,评估了摄入前和摄入后的身体组成(体重、骨骼肌质量和骨密度)和高级体能测试。结果:我们的结果显示,骨骼肌质量(p=0.039)、骨密度(p=0.020)、无脂质量指数(p=0.026)和2.4 m up and go测试(p=0.001)在测试前和测试后有显著差异。单腿站立测试前、后测试差异有统计学意义(p=0.010、p=0.049)。然而,在体脂率、小腿围、握力或椅子上升测试方面,没有显著差异。结论:一些变量在前评估和后评估中表现出显著差异,单腿站立存在交互作用。然而,这不足以证明MOP摄入对改善肌肉减少症的有效性。因此,需要更多的研究来检验MOP摄入和运动干预对患者身体成分和健康的影响。