Spinal paraganglioma presenting with raised intracranial pressure: a note on the diagnosis and post-operative management.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2024-12-01 Epub Date: 2021-12-20 DOI:10.1080/02688697.2021.2016617
Gareth May, Ajay Hegde, Claire Murphy, Edward J St George
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引用次数: 0

Abstract

Background: Spinal paragangliomas are tumors of neuroendocrine origin that present with symptoms of mass effect or neurosecretion but rarely involve the central nervous system. Raised intracranial pressure and papilledema are therefore unusual presentations of a spinal paraganglioma.

Methods: We review the case of a 54-year-old man who presented with headache and visual disturbance. Fundoscopy confirmed papilledema with normal intracranial imaging. Neuraxis imaging revealed a lumbar intradural extramedullary tumor and pathological analysis confirmed a WHO Grade I spinal paraganglioma. The tumor was resected and post operatively his vison improved with resolution of optic disc swelling.

Conclusions: Raised intracranial pressure and papilledema are unusual clinical manifestations of spinal tumors and imaging the entire neuraxis can be valuable.

出现颅内压升高的脊髓副神经节瘤:关于诊断和术后处理的说明。
背景:脊髓副神经节瘤是一种神经内分泌肿瘤,表现为肿块或神经分泌症状,但很少累及中枢神经系统。因此,颅内压升高和乳头水肿是脊髓副神经节瘤的不常见表现:我们回顾了一名 54 岁男性的病例,该患者出现头痛和视力障碍。眼底镜检查证实乳头水肿,颅内造影正常。神经影像学检查发现腰椎硬膜外肿瘤,病理分析证实为WHO I级脊髓副神经节瘤。肿瘤被切除,术后他的视力有所改善,视盘肿胀也得到了缓解:结论:颅内压升高和乳头水肿是脊柱肿瘤不常见的临床表现,对整个神经轴进行成像很有价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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