Sugarcane Bagasse as the Source of Nanocrystalline Cellulose for Gelatin-Free Capsule Shell.

IF 3 Q3 MATERIALS SCIENCE, BIOMATERIALS
International Journal of Biomaterials Pub Date : 2022-02-14 eCollection Date: 2022-01-01 DOI:10.1155/2022/9889127
Zakir Sabara, Alfirah Mutmainnah, Ummu Kalsum, Irma Nur Afiah, Ismalia Husna, Antomi Saregar, Irzaman, Rofiqul Umam
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Abstract

Gelatin-free capsules are possibly produced through an innovation which involves utilizing environmentally friendly materials derived from plants such as bagasse which are produced into nanocrystalline cellulose (NCC). This research was conducted to report the extraction and characterization of NCC from the abundant industrial plantation waste of sugarcane and its application as the base material for gelatin-free capsule shell material. The process involved using different concentrations of NCC at 1%, 2%, 4%, and 7% (in wt. %) with the addition of 1% hydroxypropyl methylcellulose (HPMC) (in wt. %) and 1% carbopol (in wt. %). Moreover, the NCC capsules obtained from sugarcane bagasse were tested for moisture content, tensile strength, elongation, solubility, and pH. The results showed that sugarcane bagasse contains 40-50% cellulose, 6.15%-9.5% moisture content which indicates they are potentially better in terms of storage, 7.25-7.85 pH, and 0.05-0.136 MPa gel strength, and the elongation value ranges from 7.19 to 87.51%. These values were discovered to have satisfied the standard requirements as indicated by the optimal concentration of 4% NCC +1% HPMC, which is in line with the Japanese Industrial Standard (JIS), thereby leading to the consideration of the material safe to be used as raw material in making capsule shells.

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甘蔗渣作为无明胶胶囊壳的纳米结晶纤维素来源。
无明胶胶囊可能是通过一种创新方法生产出来的,这种方法涉及利用从甘蔗渣等植物中提取的环保材料生产纳米结晶纤维素(NCC)。这项研究旨在报告从丰富的甘蔗工业种植废料中提取 NCC 并对其进行表征,以及将其用作无明胶胶囊外壳材料的基础材料的情况。在此过程中,使用了 1%、2%、4% 和 7%(重量百分比)不同浓度的 NCC,并添加了 1%(重量百分比)羟丙基甲基纤维素(HPMC)和 1%(重量百分比)carbopol。此外,还对甘蔗渣制成的 NCC 胶囊进行了含水量、拉伸强度、伸长率、溶解度和 pH 值测试。结果表明,甘蔗渣含有 40-50% 的纤维素、6.15%-9.5% 的含水量(这表明它们具有更好的储存潜力)、7.25-7.85 的 pH 值和 0.05-0.136 兆帕的凝胶强度,以及 7.19% 至 87.51% 的伸长值。根据最佳浓度 4% NCC +1% HPMC(符合日本工业标准 (JIS)),这些值均符合标准要求,因此可以安全地用作制造胶囊壳的原料。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
International Journal of Biomaterials
International Journal of Biomaterials MATERIALS SCIENCE, BIOMATERIALS-
CiteScore
4.30
自引率
3.20%
发文量
50
审稿时长
21 weeks
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