Incidental detection of breast cancer by 18F-fluorocholine PET/CT performed for primary hyperparathyroidism.

IF 0.6 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Vlatka Jozanovic, Drazen Huic
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引用次数: 0

Abstract

We present a case report of incidental detection of breast cancer in a female patient referred for 18F-fluorocholine (FCH) positron emission tomography/computed tomography (PET/CT) due to primary hyperparathyroidism. This imaging method was recently shown as more sensitive for the detection of metabolically hyperactive parathyroid glands than neck ultrasound and (2-metoksyizobutyloizonitryl labeled with technetium-99m) [99mTc]MIBI. Increased accumulation of FCH was found in the hyperactive parathyroid gland and unexpectedly in the right breast lesion. The surgery confirmed parathyroid adenoma. One month later right upper medial quadrantectomy confirmed breast carcinoma - a combination of invasive ductal carcinoma and intracystic papillary breast carcinoma. To the best of our knowledge, this is the first reporting of simultaneous detection of parathyroid adenoma and breast cancer by using 18F-fluorocholine PET/CT.

18f -氟胆碱PET/CT对原发性甲状旁腺功能亢进的偶然发现。
我们报告一例偶然发现乳腺癌的女性患者转介18f -氟胆碱(FCH)正电子发射断层扫描/计算机断层扫描(PET/CT)由于原发性甲状旁腺功能亢进。这种成像方法最近被证明对代谢亢进的甲状旁腺的检测比颈部超声和(2-metoksyizobutyloizonitryl标记的锝-99m) [99mTc]MIBI更敏感。在过度活跃的甲状旁腺和右侧乳腺病变中发现FCH积累增加。手术证实为甲状旁腺瘤。一个月后,右上内象限切除术证实为乳腺癌-浸润性导管癌和囊内乳头状乳腺癌合并。据我们所知,这是第一个使用18f -氟胆碱PET/CT同时检测甲状旁腺瘤和乳腺癌的报道。
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来源期刊
NUCLEAR MEDICINE REVIEW
NUCLEAR MEDICINE REVIEW RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
1.40
自引率
0.00%
发文量
53
审稿时长
24 weeks
期刊介绍: Written in English, NMR is a biannual international periodical of scientific and educational profile. It is a journal of Bulgarian, Czech, Hungarian, Macedonian, Polish, Romanian, Russian, Slovak, Ukrainian and Yugoslav Societies of Nuclear Medicine. The periodical focuses on all nuclear medicine topics (diagnostics as well as therapy), and presents original experimental scientific papers, reviews, case studies, letters also news about symposia and congresses. NMR is indexed at Index Copernicus (7.41), Scopus, EMBASE, Index Medicus/Medline, Ministry of Education 2007 (4 pts.).
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