Measurement-Based and Data-Informed Psychological Therapy.

IF 4 2区 医学 Q2 CHEMISTRY, MEDICINAL
ACS Infectious Diseases Pub Date : 2022-05-09 Epub Date: 2021-12-15 DOI:10.1146/annurev-clinpsy-071720-014821
Wolfgang Lutz, Brian Schwartz, Jaime Delgadillo
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引用次数: 26

Abstract

Outcome measurement in the field of psychotherapy has developed considerably in the last decade. This review discusses key issues related to outcome measurement, modeling, and implementation of data-informed and measurement-based psychological therapy. First, an overview is provided, covering the rationale of outcome measurement by acknowledging some of the limitations of clinical judgment. Second, different models of outcome measurement are discussed, including pre-post, session-by-session, and higher-resolution intensive outcome assessments. Third, important concepts related to modeling patterns of change are addressed, including early response, dose-response, and nonlinear change. Furthermore, rational and empirical decision tools are discussed as the foundation for measurement-based therapy. Fourth, examples of clinical applications are presented, which show great promise to support the personalization of therapy and to prevent treatment failure. Finally, we build on continuous outcome measurement as the basis for a broader understanding of clinical concepts and data-driven clinical practice in the future.

基于测量和数据的心理治疗。
在过去的十年里,心理治疗领域的结果测量有了很大的发展。这篇综述讨论了与结果测量、建模以及基于数据和测量的心理治疗的实施相关的关键问题。首先,概述了通过承认临床判断的一些局限性来涵盖结果测量的基本原理。其次,讨论了不同的结果测量模型,包括前后评估、逐次评估和更高分辨率的密集结果评估。第三,讨论了与变化模式建模相关的重要概念,包括早期响应、剂量响应和非线性变化。此外,理性和经验的决策工具,讨论为基础的测量为基础的治疗。第四,介绍了临床应用实例,显示了支持个性化治疗和预防治疗失败的巨大希望。最后,我们将持续的结果测量作为未来更广泛理解临床概念和数据驱动临床实践的基础。
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来源期刊
ACS Infectious Diseases
ACS Infectious Diseases CHEMISTRY, MEDICINALINFECTIOUS DISEASES&nb-INFECTIOUS DISEASES
CiteScore
9.70
自引率
3.80%
发文量
213
期刊介绍: ACS Infectious Diseases will be the first journal to highlight chemistry and its role in this multidisciplinary and collaborative research area. The journal will cover a diverse array of topics including, but not limited to: * Discovery and development of new antimicrobial agents — identified through target- or phenotypic-based approaches as well as compounds that induce synergy with antimicrobials. * Characterization and validation of drug target or pathways — use of single target and genome-wide knockdown and knockouts, biochemical studies, structural biology, new technologies to facilitate characterization and prioritization of potential drug targets. * Mechanism of drug resistance — fundamental research that advances our understanding of resistance; strategies to prevent resistance. * Mechanisms of action — use of genetic, metabolomic, and activity- and affinity-based protein profiling to elucidate the mechanism of action of clinical and experimental antimicrobial agents. * Host-pathogen interactions — tools for studying host-pathogen interactions, cellular biochemistry of hosts and pathogens, and molecular interactions of pathogens with host microbiota. * Small molecule vaccine adjuvants for infectious disease. * Viral and bacterial biochemistry and molecular biology.
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