{"title":"The Wolfe cycle of carbon dioxide reduction to methane revisited and the Ralph Stoner Wolfe legacy at 100 years.","authors":"William E Balch, James G Ferry","doi":"10.1016/bs.ampbs.2021.07.003","DOIUrl":null,"url":null,"abstract":"<p><p>Methanogens are a component of anaerobic microbial consortia decomposing biomass to CO<sub>2</sub> and CH<sub>4</sub> that is an essential link in the global carbon cycle. One of two major pathways of methanogenesis involves reduction of the methyl group of acetate to CH<sub>4</sub> with electrons from oxidation of the carbonyl group while the other involves reduction of CO<sub>2</sub> to CH<sub>4</sub> with electrons from H<sub>2</sub> or formate. Pioneering investigations of the CO<sub>2</sub> reduction pathway by Ralph S. Wolfe in the 70s and 80s contributed findings impacting the broader fields of biochemistry and microbiology that directed discovery of the domain Archaea and expanded research on anaerobic microbes for decades that continues to the present. This review presents an historical overview of the CO<sub>2</sub> reduction pathway (Wolfe cycle) with recent developments, and an account of Wolfe's larger and enduring impact on the broad field of biology 100 years after his birth.</p>","PeriodicalId":50953,"journal":{"name":"Advances in Microbial Physiology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in Microbial Physiology","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1016/bs.ampbs.2021.07.003","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/10/28 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"Biochemistry, Genetics and Molecular Biology","Score":null,"Total":0}
引用次数: 0
Abstract
Methanogens are a component of anaerobic microbial consortia decomposing biomass to CO2 and CH4 that is an essential link in the global carbon cycle. One of two major pathways of methanogenesis involves reduction of the methyl group of acetate to CH4 with electrons from oxidation of the carbonyl group while the other involves reduction of CO2 to CH4 with electrons from H2 or formate. Pioneering investigations of the CO2 reduction pathway by Ralph S. Wolfe in the 70s and 80s contributed findings impacting the broader fields of biochemistry and microbiology that directed discovery of the domain Archaea and expanded research on anaerobic microbes for decades that continues to the present. This review presents an historical overview of the CO2 reduction pathway (Wolfe cycle) with recent developments, and an account of Wolfe's larger and enduring impact on the broad field of biology 100 years after his birth.
产甲烷菌是将生物质分解为CO2和CH4的厌氧微生物群落的一个组成部分，是全球碳循环的一个重要环节。甲烷生成的两种主要途径之一是利用羰基氧化产生的电子将乙酸甲酯还原为CH4，另一种途径是利用H2或甲酸盐产生的电子将CO2还原为CH4。拉尔夫·s·沃尔夫(Ralph S. Wolfe)在70年代和80年代对二氧化碳减少途径的开创性研究贡献了影响生物化学和微生物学更广泛领域的发现，这些发现指导了古细菌领域的发现，并扩展了数十年来一直持续到现在的厌氧微生物研究。这篇综述介绍了二氧化碳减排途径(沃尔夫循环)的历史概况和最近的发展，以及沃尔夫在他出生100年后对生物学广泛领域的更大和持久的影响。
期刊介绍：
Advances in Microbial Physiology publishes topical and important reviews, interpreting physiology to include all material that contributes to our understanding of how microorganisms and their component parts work. First published in 1967, the editors have always striven to interpret microbial physiology in the broadest context and have never restricted the contents to traditional views of whole cell physiology.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
