Diurnal Variations in Skin Prick Testing.

IF 1.1 4区医学 Q4 ALLERGY

Pediatric Allergy Immunology and Pulmonology Pub Date : 2021-12-01 Epub Date: 2021-10-28 DOI:10.1089/ped.2021.0055

Elisa Ochfeld, Brian Cheng, Nina Bowsher, Anna Fishbein

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引用次数: 0

Abstract

Background: Prior research suggests that skin prick testing (SPT) might be larger in the afternoon, with unclear clinical significance. Methods: This retrospective chart review analyzed SPT results from patients between June 2008 and June 2017, organized into 4 time groups for analysis (Group 1: 7:00 AM -10:29 AM, Group 2: 10:30 AM -11:59 AM, Group 3: 12:00 PM -2:29 PM, and Group 4: 2:30 PM -8:15 PM). Results: In total, 12,982 (n) patient test results had positive histamine and were included in final analysis. Histamine wheal size was not significantly increased in the PM compared with AM (P = 0.89). Food allergen and aeroallergen wheal sizes were not significantly increased in PM. Histamine erythema size was increased in the PM compared with AM (P ≤ 0.01). Food allergen and aeroallergen erythema sizes trended toward an increase in the PM. Conclusions: There were not significant differences in SPT wheal size based on time of day for histamine, food allergens, or aeroallergens. SPT can be reliably performed at any time of day.

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皮肤针刺试验的日变化。

背景:先前的研究表明，皮肤点刺试验(SPT)可能在下午更大，临床意义尚不清楚。方法:回顾性分析2008年6月至2017年6月患者的SPT结果，分为4个时间组(1组:7:00 AM -10:29 AM, 2组:10:30 AM -11:59 AM, 3组:12:00 PM -2:29 PM, 4组:2:30 PM -8:15 PM)进行分析。结果:共有12982例患者组胺检测结果呈阳性，并纳入最终分析。与AM相比，PM组胺轮大小未显著增加(P = 0.89)。食物过敏原和空气过敏原的轮状大小在PM中没有显著增加。PM组胺性红斑大小比AM组胺性红斑大(P≤0.01)。食物过敏原和空气过敏原红斑的大小在PM中呈增加趋势。结论:组胺、食物过敏原或空气过敏原对SPT轮大小的影响与一天中的不同时间没有显著差异。SPT可以在一天中的任何时间可靠地执行。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pediatric Allergy Immunology and Pulmonology ALLERGY-IMMUNOLOGY

CiteScore

2.00

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Pediatric Allergy, Immunology, and Pulmonology is a peer-reviewed journal designed to promote understanding and advance the treatment of respiratory, allergic, and immunologic diseases in children. The Journal delivers original translational, clinical, and epidemiologic research on the most common chronic illnesses of children—asthma and allergies—as well as many less common and rare diseases. It emphasizes the developmental implications of the morphological, physiological, pharmacological, and sociological components of these problems, as well as the impact of disease processes on families. Pediatric Allergy, Immunology, and Pulmonology coverage includes: -Functional and genetic immune deficiencies- Interstitial lung diseases- Both common and rare respiratory, allergic, and immunologic diseases- Patient care- Patient education research- Public health policy- International health studies