Autonomic vulnerability to biased perception of social inclusion in borderline personality disorder.

IF 4 2区医学 Q1 PSYCHIATRY

Borderline Personality Disorder and Emotion Dysregulation Pub Date : 2021-11-18 DOI:10.1186/s40479-021-00169-3

Maria Lidia Gerra, Martina Ardizzi, Silvia Martorana, Veronica Leoni, Paolo Riva, Emanuele Preti, Barbara Francesca Marta Marino, Paolo Ossola, Carlo Marchesi, Vittorio Gallese, Chiara De Panfilis

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引用次数: 1

Abstract

Background: Individuals with Borderline Personality Disorder (BPD) feel rejected even when socially included. The pathophysiological mechanisms of this rejection bias are still unknown. Using the Cyberball paradigm, we investigated whether patients with BPD, display altered physiological responses to social inclusion and ostracism, as assessed by changes in Respiratory Sinus Arrhythmia (RSA).

Methods: The sample comprised 30 patients with BPD, 30 with remitted Major Depressive Disorder (rMDD) and 30 Healthy Controls (HC). Self-report ratings of threats toward one's fundamental need to belong and RSA reactivity were measured immediately after each Cyberball condition.

Results: Participants with BPD showed lower RSA at rest than HC. Only patients with BPD, reported higher threats to fundamental needs and exhibited a further decline in RSA after the Inclusion condition.

Conclusions: Individuals with BPD experience a biased appraisal of social inclusion both at the subjective and physiological level, showing higher feelings of ostracism and a breakdown of autonomic regulation to including social scenarios.

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边缘型人格障碍患者对社会包容偏见感知的自主脆弱性。

背景:边缘型人格障碍(BPD)患者即使融入社会也会感到被排斥。这种排斥偏向的病理生理机制尚不清楚。使用Cyberball范式，我们通过呼吸性窦性心律失常(RSA)的变化来评估BPD患者是否对社会包容和排斥表现出改变的生理反应。方法:30例BPD患者、30例重度抑郁障碍(rMDD)缓解者和30例健康对照(HC)。在每个赛博球条件后，立即测量对基本归属需求的威胁的自我报告评级和RSA反应。结果:BPD患者休息时的RSA低于HC。只有BPD患者报告了对基本需求的更高威胁，并且在纳入条件后RSA进一步下降。结论:BPD患者在主观和生理层面对社会包容的评价存在偏差，表现出较高的排斥感和对包括社会情景的自主调节的崩溃。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Borderline Personality Disorder and Emotion Dysregulation Psychology-Clinical Psychology

CiteScore

6.00

自引率

9.80%

发文量

审稿时长

28 weeks

期刊介绍： Borderline Personality Disorder and Emotion Dysregulation provides a platform for researchers and clinicians interested in borderline personality disorder (BPD) as a currently highly challenging psychiatric disorder. Emotion dysregulation is at the core of BPD but also stands on its own as a major pathological component of the underlying neurobiology of various other psychiatric disorders. The journal focuses on the psychological, social and neurobiological aspects of emotion dysregulation as well as epidemiology, phenomenology, pathophysiology, treatment, neurobiology, genetics, and animal models of BPD.