Uncertainty analysis for stride-time-derived modelling of lower limb stiffness: applying Taylor series expansion for error propagation on Monte-Carlo simulated data.
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引用次数: 0
Abstract
Knowledge of uncertainty is valuable mainly in correctly appraising measured effects. In lower limb stiffness, which affects injury risk and athletic performance, uncertainty is often related to vertical (Kvert) and leg (Kleg) stiffness. Imprecisions in measurements of body mass (M), leg length (L), contact (tc) and flight (tf) time propagate through the calculations, augment stiffness uncertainty and inflate relevant effects. This study estimated the limits of this uncertainty as probable (Eprob) and upper bound (Eupper) errors by applying Taylor series expansion on Monte-Carlo simulated data. Eprob and Eupper were 1285 ± 221 N/m (3.9 ± 0.2%) and 1441 ± 248 N/m (4.4 ± 0.3%) in Kvert, and 222 ± 61 N/m (2.1 ± 0.1%) and 375 ± 109 N/m (3.6 ± 0.3%) in Kleg, respectively. To avoid the complexities of full Taylor series expansion, Eprob was predicted (R2 ≈ 1) more simply as 0.89Eupper in Kvert and 11 + 0.56Eupper in Kleg. These uncertainties reflect mostly errors in tc and tf, and uncertainty in Fmax, at kinematic sampling of 300 Hz and running at 4-5 m/s. With slower sampling or faster running these uncertainties rise, and their impact on similar lower limb stiffness effects could be substantial. Applying Taylor series expansion for error propagation on Monte-Carlo simulated data is valid for uncertainty analysis in any multivariable functional relationship.
期刊介绍:
ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications.
The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.