Oral nonsteroidal anti-inflammatory drugs as treatment of joint and muscle pain in temporomandibular disorders: A systematic review.

IF 4.7 Q2 MATERIALS SCIENCE, BIOMATERIALS

ACS Applied Bio Materials Pub Date : 2024-11-01 Epub Date: 2022-02-07 DOI:10.1080/08869634.2022.2031688

Federica Montinaro, Ludovica Nucci, Fabrizia d'Apuzzo, Letizia Perillo, Maria Chiara Chiarenza, Vincenzo Grassia

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引用次数: 0

Abstract

Objective: To evaluate pain control in patients with joint and muscle pain in temporomandibular disorder (TMD) diagnosis treated with oral non-steroidal anti-inflammatory drugs (NSAIDs).

Methods: The systematic research was conducted via Pubmed, Scopus, Web of Science, Google Scholar, and Cochrane databases.

Results: Four full-text randomized-controlled trials (RCTs) were considered eligible. This systematic review included 164 patients whose VAS scores were assessed before and after therapy. In the selected studies, a strong heterogeneity in the diagnosis and in the use of different types and prescriptions of NSAIDs was highlighted. These limitations had to be considered to understand whether a clinical recommendation could be made. Eventually, all patients treated with NSAIDs showed an improvement in pain.

Conclusion: The use of oral NSAIDs as the first approach to control joint and muscle pain is sustained by the current scientific literature, but further investigations on this topic are still needed.

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口服非甾体抗炎药治疗颞下颌关节紊乱症的关节和肌肉疼痛：系统综述。

目的评估口服非甾体抗炎药（NSAIDs）治疗颞下颌关节紊乱症（TMD）诊断中关节和肌肉疼痛患者的疼痛控制情况：通过Pubmed、Scopus、Web of Science、Google Scholar和Cochrane数据库进行系统研究：结果：四项全文随机对照试验（RCT）被认为符合条件。该系统性综述纳入了 164 名患者，对其治疗前后的 VAS 评分进行了评估。在所选研究中，诊断以及使用不同类型和处方的非甾体抗炎药的异质性很强。必须考虑到这些局限性，才能了解是否可以提出临床建议。最终，所有接受非甾体抗炎药治疗的患者的疼痛都得到了改善：结论：目前的科学文献支持将口服非甾体抗炎药作为控制关节和肌肉疼痛的首选方法，但仍需对此进行进一步研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Applied Bio Materials Chemistry-Chemistry (all)

CiteScore

9.40

自引率

2.10%

发文量

464

期刊介绍： ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.