A Case of Localized Prostate Cancer Associated with Polymyalgia Rheumatica with Marked Symptomatic Improvement after Robot-Assisted Radical Prostatectomy.

Case Reports in Urology Pub Date : 2021-10-15 eCollection Date: 2021-01-01 DOI:10.1155/2021/8026883
Makoto Kawase, Keita Nakane, Sanae Namiki, Yasumichi Takeuchi, Shota Ueda, Kota Kawase, Chie Nakai, Shinichi Takeuchi, Daiki Kato, Manabu Takai, Koji Iinuma, Masayuki Fuwa, Chiemi Saigo, Tatsuhiko Miyazaki, Hiroyuki Morita, Takuya Koie
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引用次数: 1

Abstract

A 73-year-old man visited our hospital with chief complaints of fever of unknown origin and bilateral shoulder and hip joint pain. He was initially diagnosed with polymyalgia rheumatica (PMR). Although the patient was treated with prednisolone 15 mg/day, his PMR-related symptoms did not improve. Further examination was performed as the patient was suspected of having paraneoplastic syndrome. Assessment results showed prostate cancer without metastases. After undergoing robot-assisted radical prostatectomy, the patient's PMR-related symptoms dramatically improved. Hence, the prednisolone dose was decreased to 4 mg/day. PCa may have triggered the development of PMR through the activation of immune-mediated systemic inflammatory responses.

Abstract Image

Abstract Image

局部前列腺癌伴风湿性多肌痛1例,机器人辅助根治性前列腺切除术后症状明显改善。
一名73岁男性以不明原因发热和双侧肩关节及髋关节疼痛为主诉来我院就诊。他最初被诊断为风湿病多肌痛(PMR)。尽管患者接受了15毫克/天的强的松龙治疗,但其pmr相关症状并未改善。由于怀疑患者患有副肿瘤综合征,我们进行了进一步的检查。评估结果显示前列腺癌无转移。在接受机器人辅助根治性前列腺切除术后,患者的pmr相关症状显著改善。因此,泼尼松龙的剂量减少到4mg /天。PCa可能通过激活免疫介导的全身炎症反应而引发PMR的发展。
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