Prevalence of Hepatitis B Carrier Status and Its Negative Association with Hypertensive Disorders in Pregnancy.

IF 1.6 Q3 OBSTETRICS & GYNECOLOGY

Obstetrics and Gynecology International Pub Date : 2021-10-13 eCollection Date: 2021-01-01 DOI:10.1155/2021/9912743

W Y Lok, C W Kong, W W K To

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引用次数: 4

Abstract

Results: In a total cohort of 87889 deliveries over a period of 20 years, the prevalence rate of HBV fell from around 10-11% to around 6-7% in the last 5 years of the study. A negative association between chronic HBV carrier status and all gestational hypertensive disorders could be demonstrated. An apparent protective effect of HBV carrier status was apparently more robust against preeclampsia than gestational hypertension, as the negative association with preeclampsia was consistently observed throughout the study period. A logistic regression model showed that advanced maternal age, multiple pregnancies, obesity, and significant medical disorders were positively correlated with gestational hypertensive disorders, while multiparity and positive HBV carrier status were negatively correlated.

Conclusion: Chronic HBV carrier status appeared to have a protective effect against the development of preeclampsia and gestational hypertension in an endemic area with high HBV prevalence rates.

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妊娠期乙型肝炎携带者的患病率及其与高血压疾病的负相关

结果:在一项为期20年的共87889例分娩队列中，HBV的患病率在研究的最后5年从约10-11%下降到约6-7%。慢性乙型肝炎病毒携带者状态与所有妊娠期高血压疾病之间存在负相关。HBV携带者对子痫前期的保护作用明显强于妊娠期高血压，因为在整个研究期间一直观察到HBV携带者与子痫前期的负相关。logistic回归模型显示，高龄产妇、多胎、肥胖、重大医学疾病与妊娠期高血压疾病呈正相关，多胎与HBV阳性携带者呈负相关。结论:在HBV高发地区，慢性HBV携带者对子痫前期和妊娠期高血压的发生具有保护作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Obstetrics and Gynecology International OBSTETRICS & GYNECOLOGY-

CiteScore

3.60

自引率

0.00%

发文量

审稿时长

19 weeks

期刊介绍： Obstetrics and Gynecology International is a peer-reviewed, Open Access journal that aims to provide a forum for scientists and clinical professionals working in obstetrics and gynecology. The journal publishes original research articles, review articles, and clinical studies related to obstetrics, maternal-fetal medicine, general gynecology, gynecologic oncology, uro-gynecology, reproductive medicine and infertility, reproductive endocrinology, and sexual medicine.