Synthetic biology open language visual (SBOL visual) version 3.0.

IF 1.5 Q3 MATHEMATICAL & COMPUTATIONAL BIOLOGY
Hasan Baig, Pedro Fontanarossa, James McLaughlin, James Scott-Brown, Prashant Vaidyanathan, Thomas Gorochowski, Goksel Misirli, Jacob Beal, Chris Myers
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引用次数: 10

Abstract

People who engineer biological organisms often find it useful to draw diagrams in order to communicate both the structure of the nucleic acid sequences that they are engineering and the functional relationships between sequence features and other molecular species. Some typical practices and conventions have begun to emerge for such diagrams. SBOL Visual aims to organize and systematize such conventions in order to produce a coherent language for expressing the structure and function of genetic designs. This document details version 3.0 of SBOL Visual, a new major revision of the standard. The major difference between SBOL Visual 3 and SBOL Visual 2 is that diagrams and glyphs are defined with respect to the SBOL 3 data model rather than the SBOL 2 data model. A byproduct of this change is that the use of dashed undirected lines for subsystem mappings has been removed, pending future determination on how to represent general SBOL 3 constraints; in the interim, this annotation can still be used as an annotation. Finally, deprecated material has been removed from collection of glyphs: the deprecated "insulator" glyph and "macromolecule" alternative glyphs have been removed, as have the deprecated BioPAX alternatives to SBO terms.

合成生物学开放语言可视化(SBOL可视化)3.0版。
设计生物有机体的人经常发现,绘制图表是很有用的,这样既可以说明他们正在设计的核酸序列的结构,也可以说明序列特征与其他分子物种之间的功能关系。对于这样的图,一些典型的实践和惯例已经开始出现。SBOL Visual旨在组织和系统化这些约定,以便产生一种连贯的语言来表达遗传设计的结构和功能。本文档详细介绍了SBOL Visual 3.0版本,这是该标准的一个新的主要修订。SBOL Visual 3和SBOL Visual 2之间的主要区别在于,图表和符号是根据SBOL 3数据模型而不是SBOL 2数据模型定义的。这一变化的一个副产品是取消了对子系统映射的虚线无向线的使用,这有待于未来如何表示通用SBOL 3约束的决定;在此期间,该注释仍然可以作为注释使用。最后,已从字形集合中删除了已弃用的材料:已弃用的“绝缘体”字形和“大分子”替代字形已被删除,以及已弃用的BioPAX替代SBO术语。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Integrative Bioinformatics
Journal of Integrative Bioinformatics Medicine-Medicine (all)
CiteScore
3.10
自引率
5.30%
发文量
27
审稿时长
12 weeks
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