A mini-review on peptide-based self-assemblies and their biological applications.

IF 2.9 4区材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY

Nanotechnology Pub Date : 2021-11-16 DOI:10.1088/1361-6528/ac2fe3

Chenlei Wang, Linping Fu, Zhiyuan Hu, Yeteng Zhong

引用次数: 10

Abstract

Peptide-based supramolecular self-assembly from peptide monomers into well-organized nanostructures, has attracted extensive attentions towards biomedical and biotechnological applications in recent decades. This spontaneous and reversible assembly process involving non-covalent bonding interactions can be artificially regulated. In this review, we have elaborated different strategies to modulate the peptide self-assembly through tuning the physicochemical and environmental conditions, includingpH, light, temperature, solvent, and enzyme. Detailed introduction of biological applications and future potential of the peptide-based nano-assemblies will also be given.

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基于肽的自组装及其生物学应用综述。

近几十年来，基于肽的超分子自组装技术在生物医学和生物技术领域得到了广泛的关注。这种涉及非共价键相互作用的自发可逆组装过程可以人为调节。在这篇综述中，我们阐述了通过调整物理化学和环境条件来调节肽自组装的不同策略，包括ph、光、温度、溶剂和酶。详细介绍了肽基纳米组件的生物学应用和未来潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nanotechnology 工程技术-材料科学：综合

CiteScore

7.10

自引率

5.70%

发文量

820

审稿时长

2.5 months

期刊介绍： The journal aims to publish papers at the forefront of nanoscale science and technology and especially those of an interdisciplinary nature. Here, nanotechnology is taken to include the ability to individually address, control, and modify structures, materials and devices with nanometre precision, and the synthesis of such structures into systems of micro- and macroscopic dimensions such as MEMS based devices. It encompasses the understanding of the fundamental physics, chemistry, biology and technology of nanometre-scale objects and how such objects can be used in the areas of computation, sensors, nanostructured materials and nano-biotechnology.