Acute Cerebellitis in MIS-C: A Case Report.

The Pediatric Infectious Disease Journal Pub Date : 2022-01-01 DOI:10.1097/INF.0000000000003358

Nihal Akçay, Mustafa Oğur, Mehmet Emin Menentoğlu, Ayşe İrem Sofuoğlu, Kübra Boydağ Güvenç, Figen Bakirtaş Palabiyik, Esra Şevketoğlu

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引用次数: 5

Abstract

Background: Coronavirus disease-2019 (COVID-19) is characterized predominantly by respiratory symptoms and has affected a small subset of children. Multisystem inflammatory syndrome in children (MIS-C) has been reported in children following COVID-19. There is increasing report that COVID-19 may also lead to neurologic manifestations. Cerebellar lesions may be observed in viral infections.

Case report: We report a child with MIS-C related to severe acute respiratory syndrome coronavirus 2, who developed cerebellar lesion during the disease course. Encephalopathy was the first central nervous system symptom. His consciousness improved but he developed clinical signs of cerebellar dysfunction including ataxia, dysarthria and nystagmus. Brain magnetic resonance imaging (MRI) revealed symmetrical pathological signal changes in both cerebellar hemispheres.

Conclusion: We demonstrated the first child with MIS-C to develop cerebellar lesion on brain MRI, suggestive of cerebellitis.

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misc型急性小脑炎1例报告。

背景:冠状病毒病-2019 (COVID-19)主要以呼吸道症状为特征，并影响了一小部分儿童。儿童多系统炎症综合征(MIS-C)在COVID-19患儿中有报道。越来越多的报告显示，COVID-19还可能导致神经系统症状。病毒感染可引起小脑病变。病例报告:我们报告1例与严重急性呼吸综合征冠状病毒2相关的misc患儿，在病程中出现小脑病变。脑病是第一中枢神经系统症状。他的意识有所改善，但出现小脑功能障碍的临床症状，包括共济失调、构音障碍和眼球震颤。脑磁共振成像(MRI)显示在两个小脑半球对称的病理信号改变。结论:我们证实了第一个在脑MRI上出现小脑损伤的misc患儿，提示小脑炎。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The Pediatric Infectious Disease Journal

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