Sagar Mahendrabhai Bhinde, Sonam Sagar Bhinde, Virendra K Kori, Kalpana S Patel
{"title":"A compendious review of <i>Chitraka Haritaki Avaleha</i> - A polyherbal <i>Ayurveda</i> formulation for bronchial asthma.","authors":"Sagar Mahendrabhai Bhinde, Sonam Sagar Bhinde, Virendra K Kori, Kalpana S Patel","doi":"10.4103/ayu.AYU_340_20","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong><i>Avaleha</i> (confection) is an unique dosage form of Ayurvedic pharmaceutics, which is frequently prescribed in various disorders and especially in respiratory disorders. <i>Chitraka</i> <i>Haritaki</i> <i>Avaleha</i> (CHA) is one such formulation being used extensively by <i>Ayurveda</i> physicians for bronchial asthma, despite its classical use in various other disorders too. CHA was first time described by Vrindamadhava in the 9<sup>th</sup> century and had been amended for many times till today. Because of its demand, many pharmaceutical companies are also manufacturing it, and is freely available in the market.</p><p><strong>Aim: </strong>The aim is to screen and compile references pertaining to composition, method of preparation, therapeutic uses, organoleptic, and physico-chemical parameters of CHA from different classics and original research articles.</p><p><strong>Materials and methods: </strong>Description of CHA was extensively reviewed from Vrindamadhava, Chakradatta, Vangasena, Gadanigraha, Yogatarangini, Bhaishjya Ratnavali and Yogaratnakara. Synonyms, <i>Rasapanchaka</i> (<i>Ayurveda</i> principles of drug action), and <i>Dosha</i> <i>Karma</i> (therapeutic attributes) of ingredients were compiled from Bhavaprakasha Nighantu. Organoleptic and physicochemical parameters were compiled from original research articles, searched from PubMed, Google Scholar, and Research Gate.</p><p><strong>Results: </strong>Variations in formulation name, ingredients, method of preparation, therapeutic indications and <i>Anupana</i> (adjuvant) was observed in the classical texts. Value of water-soluble extracts and pH of analytical study was found different than <i>Ayurveda</i> Pharmacopeia of India standards.</p><p><strong>Conclusion: </strong>Screening through various texts revealed that CHA has been mentioned in seven classical treatises and two gazetted texts with amendments which indicate its high demand and clinical efficacy in bronchial asthma along with other diseases. Disparity found in analytical parameters indicates the need of standardization of pharmaceutical process.</p>","PeriodicalId":8720,"journal":{"name":"Ayu","volume":"41 1","pages":"12-18"},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c0/a2/AYU-41-12.PMC8415241.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ayu","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/ayu.AYU_340_20","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/7/30 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: Avaleha (confection) is an unique dosage form of Ayurvedic pharmaceutics, which is frequently prescribed in various disorders and especially in respiratory disorders. ChitrakaHaritakiAvaleha (CHA) is one such formulation being used extensively by Ayurveda physicians for bronchial asthma, despite its classical use in various other disorders too. CHA was first time described by Vrindamadhava in the 9th century and had been amended for many times till today. Because of its demand, many pharmaceutical companies are also manufacturing it, and is freely available in the market.
Aim: The aim is to screen and compile references pertaining to composition, method of preparation, therapeutic uses, organoleptic, and physico-chemical parameters of CHA from different classics and original research articles.
Materials and methods: Description of CHA was extensively reviewed from Vrindamadhava, Chakradatta, Vangasena, Gadanigraha, Yogatarangini, Bhaishjya Ratnavali and Yogaratnakara. Synonyms, Rasapanchaka (Ayurveda principles of drug action), and DoshaKarma (therapeutic attributes) of ingredients were compiled from Bhavaprakasha Nighantu. Organoleptic and physicochemical parameters were compiled from original research articles, searched from PubMed, Google Scholar, and Research Gate.
Results: Variations in formulation name, ingredients, method of preparation, therapeutic indications and Anupana (adjuvant) was observed in the classical texts. Value of water-soluble extracts and pH of analytical study was found different than Ayurveda Pharmacopeia of India standards.
Conclusion: Screening through various texts revealed that CHA has been mentioned in seven classical treatises and two gazetted texts with amendments which indicate its high demand and clinical efficacy in bronchial asthma along with other diseases. Disparity found in analytical parameters indicates the need of standardization of pharmaceutical process.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
