Biological activities of some Salvia species.

IF 2.1 4区生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

Zeitschrift Fur Naturforschung Section C-A Journal of Biosciences Pub Date : 2021-09-20 Print Date: 2022-03-28 DOI:10.1515/znc-2021-0136

Mehmet Doğan, Nurdan Akıcı, Mehmet Emin Diken, Serap Doğan, Begumhan Yilmaz Kardas, Tuncay Dirmenci

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引用次数: 1

Abstract

In this study, total phenolic, flavonoid and protein contents, antiradical capacities, antibacterial and cytotoxic properties of five different Salvia species (Salvia macrochlamys Boiss., Salvia kronenburgii Rech.f., Salvia euphratica Montbret. ex Aucher var. euphratica, Salvia huberi Hedge and Salvia kurdica Benth) were investigated. The total phenolic content of the species was in the range of 59.6 ± 20 to 150.1 ± 1.1 mg/g, total flavonoid content in the range of 20.4 ± 2.2 to 38.9 ± 4.1 mg/g, and total protein content in the range of 14.0 ± 0.5 to 22.0 ± 1.1 mg/g. Radical scavenging capacities of the Salvia species were determined in the range of 84.1 ± 4.5 to 96.8 ± 0.1%. Moreover, Salvia extracts showed powerful antibacterial activity against Escherichia coli and Staphylococcus aureus bacteria. Cytotoxic effects of the samples on human lymphocytes were determined by MTS assay and S. kronenburgii and S. euphratica var. euphratica decreased the harmful effects of 2-hydroperoxy-2-methylpropane (tert-butyl hydroper-oxide, t-BOOH) at all time points tested. The highest amounts of rutin hydrate belong to S. kronenburgii and S. euphratica var. euphratica, and the highest amounts of luteolin-7-glucoside belong to S. huberi and S. kronenburgii. Vanillic acid was present only in S. huberi and S. kurdica.

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几种鼠尾草的生物活性。

本文对五种不同鼠尾草(Salvia macrochlamys Boiss)的总酚、类黄酮和蛋白质含量、抗自由基能力、抗菌和细胞毒性进行了研究。鼠尾草(Salvia kronenburgii rech .);，鼠尾草。以胡杨、小黄鼠尾草和小黄鼠尾草为研究对象。总酚含量为59.6±20 ~ 150.1±1.1 mg/g，总黄酮含量为20.4±2.2 ~ 38.9±4.1 mg/g，总蛋白含量为14.0±0.5 ~ 22.0±1.1 mg/g。丹参对自由基的清除能力在84.1±4.5 ~ 96.8±0.1%范围内。此外，鼠尾草提取物对大肠杆菌和金黄色葡萄球菌具有较强的抗菌活性。采用MTS法测定样品对人淋巴细胞的细胞毒作用，发现kronenburgii和S. euphratica var. euphratica在测试的所有时间点都降低了2-羟基过氧化氢-2-甲基丙烷(叔丁基氢氧化物，t-BOOH)的有害作用。水合芦丁含量最高的是胡柏和胡杨，木犀草和胡杨的木犀草素-7-糖苷含量最高。香草酸仅存在于胡贝尔花和库尔迪花中。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Zeitschrift Fur Naturforschung Section C-A Journal of Biosciences 生物-生化与分子生物学

CiteScore

4.10

自引率

5.00%

发文量

期刊介绍： A Journal of Biosciences: Zeitschrift für Naturforschung C (ZNC) is an international scientific journal and a community resource for the emerging field of natural and natural-like products. The journal publishes original research on the isolation (including structure elucidation), bio-chemical synthesis and bioactivities of natural products, their biochemistry, pharmacology, biotechnology, and their biological activity and innovative developed computational methods for predicting the structure and/or function of natural products. A Journal of Biosciences: Zeitschrift für Naturforschung C (ZNC) welcomes research papers in fields on the chemistry-biology boundary which address scientific ideas and approaches to generate and understand natural compounds on a molecular level and/or use them to stimulate and manipulate biological processes.