Splitting the Total Dose of Cyclophosphamide in Two Blocks Apart during the Conditioning of Autologous Hematopoietic Stem Cell Transplantation in Multiple Sclerosis Results in Diminished Cardiotoxicity: Experience in 1,000 Patients.

IF 1.4 4区医学 Q2 Medicine

Revista De Investigacion Clinica-Clinical and Translational Investigation Pub Date : 2022-01-03 DOI:10.24875/RIC.21000206

Juan Carlos Olivares-Gazca, Francisco Guerrero-Pesqueira, Iván Murrieta-Alvarez, Yahveth Cantero-Fortiz, Andrés A León-Peña, José M Priesca-Marín, David Gomez-Almaguer, Andrés Gomez-De-Leon, Guillermo J Ruiz-Delgado, Guillermo J Ruiz-Argüelles

引用次数: 0

Abstract

Autologous hematopoietic stem cell transplantation (HSCT) has been given to persons with multiple sclerosis (MS) for over 20 years, and more than 3000 HSCTs have been done worldwide1,2. Transplant-related mortality in MS managed with HSCT, was considered a limiting factor but has decreased to < 2%2.

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在多发性硬化症患者自体造血干细胞移植适应症中，将环磷酰胺总剂量分成两组可降低心脏毒性:1000例患者的经验

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Revista De Investigacion Clinica-Clinical and Translational Investigation 医学-医学：内科

CiteScore

3.00

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The Revista de Investigación Clínica – Clinical and Translational Investigation (RIC-C&TI), publishes original clinical and biomedical research of interest to physicians in internal medicine, surgery, and any of their specialties. The Revista de Investigación Clínica – Clinical and Translational Investigation is the official journal of the National Institutes of Health of Mexico, which comprises a group of Institutes and High Specialty Hospitals belonging to the Ministery of Health. The journal is published both on-line and in printed version, appears bimonthly and publishes peer-reviewed original research articles as well as brief and in-depth reviews. All articles published are open access and can be immediately and permanently free for everyone to read and download. The journal accepts clinical and molecular research articles, short reports and reviews. Types of manuscripts: – Brief Communications – Research Letters – Original Articles – Brief Reviews – In-depth Reviews – Perspectives – Letters to the Editor