Assessment of a Cationic Emulsion to Control the Tear Film Evaporation Rate.

IF 1.4 Q3 OPHTHALMOLOGY

Clinical Optometry Pub Date : 2021-08-11 eCollection Date: 2021-01-01 DOI:10.2147/OPTO.S328787

Ali Abusharha

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Abstract

Purpose: To investigate the effect of a single application of cationic emulsion in controlling tear film evaporation and improving tear quality and quantity.

Materials a methods: Twenty male subjects diagnosed with DE were enrolled in the study with an average age of 45.8 ± 6.37 years. The tear film parameters were observed at several time points post-instillation of the cationic emulsion (10, 20, 30, and 60 min). The tear evaporation rate (TER) was measured with a VapoMeter. Noninvasive tear break-up time and meniscus height were assessed using OCULUS Keratograph.

Results: TER decreased by more than 20% at 20, 30, and 60 minutes time points after instillation of single drop of cationic emulsion. Also, a significant improvement in tear film stability was found at all time points following the instillation of cationic emulsion eye drops. The mean tear break-up time increased from 5.55 ± 2.87 to 6.6 ± 4.2 sec at 60 minutes. The maximum increase in tear break-up time occurred at 30 minutes time point. The TMH was also significantly higher post-instillation of oil emulsion eye drops. There was a significant increase in the TMH post-therapy with oil drop at all time points.

Conclusion: The overall study findings of this study illustrate that the single application of a cationic emulsion effectively controls tear film evaporation in patients with mild to moderate DEs. The cationic emulsion efficiently enhanced both the tear film stability and the tear meniscus volume.

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评估控制泪膜蒸发率的阳离子乳液

目的：研究单次使用阳离子乳液对控制泪膜蒸发、改善泪液质量和数量的影响：研究对象为 20 名确诊为 DE 的男性，平均年龄（45.8 ± 6.37）岁。在注入阳离子乳液后的几个时间点（10、20、30 和 60 分钟）观察泪膜参数。泪液蒸发率（TER）是用蒸发仪测量的。使用 OCULUS 角膜塑形仪评估无创泪液破裂时间和半月板高度：结果：滴入一滴阳离子乳液后，在 20 分钟、30 分钟和 60 分钟的时间点上，泪液蒸发率下降了 20% 以上。此外，在滴入阳离子乳液眼药水后的所有时间点，泪膜稳定性都有明显改善。平均泪液破裂时间从 5.55 ± 2.87 秒增加到 60 分钟时的 6.6 ± 4.2 秒。泪液破裂时间的最大增幅出现在 30 分钟时点。滴入油乳剂眼药水后，泪液分离时间也明显增加。结论：本研究的总体结果表明，滴用油性乳剂眼药水后，泪液破裂时间明显缩短：本研究的总体结果表明，单次使用阳离子乳液可有效控制轻度至中度 DE 患者的泪膜蒸发。阳离子乳液有效提高了泪膜的稳定性和泪液半月板的体积。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Optometry OPHTHALMOLOGY-

CiteScore

3.00

自引率

5.90%

发文量

审稿时长

16 weeks

期刊介绍： Clinical Optometry is an international, peer-reviewed, open access journal focusing on clinical optometry. All aspects of patient care are addressed within the journal as well as the practice of optometry including economic and business analyses. Basic and clinical research papers are published that cover all aspects of optics, refraction and its application to the theory and practice of optometry. Specific topics covered in the journal include: Theoretical and applied optics, Delivery of patient care in optometry practice, Refraction and correction of errors, Screening and preventative aspects of eye disease, Extended clinical roles for optometrists including shared care and provision of medications, Teaching and training optometrists, International aspects of optometry, Business practice, Patient adherence, quality of life, satisfaction, Health economic evaluations.