Xiao Yang, Zhouxiang You, Yue Chen, Tianyang Dai, Huipan Liu
{"title":"Thymic squamous cell carcinoma mimicking lymphoma on 68Ga-FAPI PET/CT.","authors":"Xiao Yang, Zhouxiang You, Yue Chen, Tianyang Dai, Huipan Liu","doi":"10.1055/a-1561-2014","DOIUrl":null,"url":null,"abstract":"A 33-year-old man presented with progressive enlargement of supraclavicular fossa mass for 2 years. Recently, the patient feels neck pain when swallowing food. Previous chest CT imaging revealed an anterior mediastinal soft tissue mass without any evidence for adjacent vascular or lung invasion (approximately 4.1 cm × 3.4 cm in size), indicating a mediastinal tumor; therefore, malignancy could not be ruled out. With the consent of the patient, we enrolled him in a clinical trial of 68Ga-FAPI-04 PET/CT in tumors (ChiCTR2100044131). 68Ga-FAPI-04 PET/CT scan (▶ Fig. 1A-D) detected that the anterior mediastinal mass had intense FAPI uptake (SUVmax of 12.0). Based on these PET/CT findings, the lesion was suspected to be a mediastinal lymphoma. Subsequently, the patient underwent surgical resection of soft tissue mass. Immunohistochemistry revealed CK (+), CK19 (+), P63 (+), CD1a (+), TdT (+), CD5 (+), CD20 (+), CD117 (+), P53 (+, 50 %), Ki-67 (+, 40 %). However, the findings were consistent with thymic squamous cell carcinoma (SCC). Finally, the patient was well at the six-month follow-up visit.","PeriodicalId":19238,"journal":{"name":"Nuklearmedizin-nuclear Medicine","volume":null,"pages":null},"PeriodicalIF":1.0000,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nuklearmedizin-nuclear Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1055/a-1561-2014","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/8/17 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 1
Abstract
A 33-year-old man presented with progressive enlargement of supraclavicular fossa mass for 2 years. Recently, the patient feels neck pain when swallowing food. Previous chest CT imaging revealed an anterior mediastinal soft tissue mass without any evidence for adjacent vascular or lung invasion (approximately 4.1 cm × 3.4 cm in size), indicating a mediastinal tumor; therefore, malignancy could not be ruled out. With the consent of the patient, we enrolled him in a clinical trial of 68Ga-FAPI-04 PET/CT in tumors (ChiCTR2100044131). 68Ga-FAPI-04 PET/CT scan (▶ Fig. 1A-D) detected that the anterior mediastinal mass had intense FAPI uptake (SUVmax of 12.0). Based on these PET/CT findings, the lesion was suspected to be a mediastinal lymphoma. Subsequently, the patient underwent surgical resection of soft tissue mass. Immunohistochemistry revealed CK (+), CK19 (+), P63 (+), CD1a (+), TdT (+), CD5 (+), CD20 (+), CD117 (+), P53 (+, 50 %), Ki-67 (+, 40 %). However, the findings were consistent with thymic squamous cell carcinoma (SCC). Finally, the patient was well at the six-month follow-up visit.
期刊介绍:
Als Standes- und Fachorgan (Organ von Deutscher Gesellschaft für Nuklearmedizin (DGN), Österreichischer Gesellschaft für Nuklearmedizin und Molekulare Bildgebung (ÖGN), Schweizerischer Gesellschaft für Nuklearmedizin (SGNM, SSNM)) von hohem wissenschaftlichen Anspruch befasst sich die CME-zertifizierte Nuklearmedizin/ NuclearMedicine mit Diagnostik und Therapie in der Nuklearmedizin und dem Strahlenschutz: Originalien, Übersichtsarbeiten, Referate und Kongressberichte stellen aktuelle Themen der Diagnose und Therapie dar.
Ausführliche Berichte aus den DGN-Arbeitskreisen, Nachrichten aus Forschung und Industrie sowie Beschreibungen innovativer technischer Geräte, Einrichtungen und Systeme runden das Konzept ab.
Die Abstracts der Jahrestagungen dreier europäischer Fachgesellschaften sind Bestandteil der Kongressausgaben.
Nuklearmedizin erscheint regelmäßig mit sechs Ausgaben pro Jahr und richtet sich vor allem an Nuklearmediziner, Radiologen, Strahlentherapeuten, Medizinphysiker und Radiopharmazeuten.