Diagnosis of Menière's disease according to the criteria of 2015: Characteristics and challenges in 96 patients.

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS

ACS Applied Bio Materials Pub Date : 2022-01-01 DOI:10.3233/VES-201634

Friedrich Ihler, Ivelina Stoycheva, Jennifer L Spiegel, Daniel Polterauer, Joachim Müller, Ralf Strobl, Eva Grill

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引用次数: 2

Abstract

Background: The diagnosis of Menière's disease (MD) is made according to diagnostic criteria, the last revision of which was in 2015. For diagnosis, symptoms are weighted with audiometric findings and this can be challenging in individual patients.

Objective: To analyze patient's characteristics and symptoms in a real-life cohort of 96 patients with diagnosed MD regarding sociodemographic parameters, clinical specifics, and audiometry.

Methods: Prospective clinical patient registry containing demographic and socioeconomic parameters, symptoms, as well as pure-tone audiometry data.

Results: 31 patients with definite MD, and 36 with probable MD were identified. 29 patients showed typical clinical signs of MD, but did not meet the full diagnostic criteria, and were considered separately. Mean duration of symptoms prior to presentation was 3.9±4.6 years. Significant differences between categories were found regarding aural fullness, tinnitus, and fluctuating hearing. If multiple audiograms were available, 28.6 % (6/21) documented fluctuating hearing.

Conclusions: Current diagnostic criteria probably do not represent patients with monosymptomatic presentation or an early stage very well. Long-term follow-up with repeated audiometry is advisable.

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根据2015年标准诊断meni病:96例患者的特点和挑战

背景:meni氏病(MD)的诊断是根据诊断标准进行的，上一次修订是在2015年。对于诊断，症状与听力检查结果加权，这在个别患者中可能具有挑战性。目的:分析96例诊断为MD的患者的社会人口学参数、临床特征和听力测定的特征和症状。方法:前瞻性临床患者登记包含人口统计学和社会经济参数，症状，以及纯音听力学数据。结果:确诊MD 31例，疑似MD 36例。29例患者表现出典型的MD临床症状，但不符合全部诊断标准，单独考虑。症状出现前的平均持续时间为3.9±4.6年。在听力充盈、耳鸣和波动听力方面，不同类别之间存在显著差异。如果有多种听音图，28.6%(6/21)的人记录了波动的听力。结论:目前的诊断标准可能不能很好地代表单症状表现或早期阶段的患者。建议长期随访反复听力学。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Applied Bio Materials Chemistry-Chemistry (all)

CiteScore

9.40

自引率

2.10%

发文量

464

期刊介绍： ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.