Friedrich Ihler, Ivelina Stoycheva, Jennifer L Spiegel, Daniel Polterauer, Joachim Müller, Ralf Strobl, Eva Grill
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引用次数: 2
Abstract
Background: The diagnosis of Menière's disease (MD) is made according to diagnostic criteria, the last revision of which was in 2015. For diagnosis, symptoms are weighted with audiometric findings and this can be challenging in individual patients.
Objective: To analyze patient's characteristics and symptoms in a real-life cohort of 96 patients with diagnosed MD regarding sociodemographic parameters, clinical specifics, and audiometry.
Methods: Prospective clinical patient registry containing demographic and socioeconomic parameters, symptoms, as well as pure-tone audiometry data.
Results: 31 patients with definite MD, and 36 with probable MD were identified. 29 patients showed typical clinical signs of MD, but did not meet the full diagnostic criteria, and were considered separately. Mean duration of symptoms prior to presentation was 3.9±4.6 years. Significant differences between categories were found regarding aural fullness, tinnitus, and fluctuating hearing. If multiple audiograms were available, 28.6 % (6/21) documented fluctuating hearing.
Conclusions: Current diagnostic criteria probably do not represent patients with monosymptomatic presentation or an early stage very well. Long-term follow-up with repeated audiometry is advisable.
期刊介绍:
Journal of Vestibular Research is a peer-reviewed journal that publishes experimental and observational studies, review papers, and theoretical papers based on current knowledge of the vestibular system. Subjects of the studies can include experimental animals, normal humans, and humans with vestibular or other related disorders. Study topics can include the following:
Anatomy of the vestibular system, including vestibulo-ocular, vestibulo-spinal, and vestibulo-autonomic pathways
Balance disorders
Neurochemistry and neuropharmacology of balance, both at the systems and single neuron level
Neurophysiology of balance, including the vestibular, ocular motor, autonomic, and postural control systems
Psychophysics of spatial orientation
Space and motion sickness
Vestibular rehabilitation
Vestibular-related human performance in various environments