Indicator-focussed technical assistance in South Africa's HIV programme: A stepped-wedge evaluation.

IF 2.3 4区 医学 Q4 INFECTIOUS DISEASES
Southern African Journal of Hiv Medicine Pub Date : 2021-06-15 eCollection Date: 2021-01-01 DOI:10.4102/sajhivmed.v22i1.1229
Geoffrey A Jobson, Jean Railton, Barry Mutasa, Lucy Ranoto, Christine Maluleke, James McIntyre, Helen Struthers, Remco Peters
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引用次数: 0

Abstract

Background: There is a lack of research on technical assistance (TA) interventions in low- and middle-income countries. Variation in local contexts requires tailor-made approaches to TA that are structured and replicable across intervention sites whilst retaining the flexibility to adapt to local contexts. We developed a systematic process of TA using multidisciplinary roving teams to provide support across the various elements comprising local HIV services.

Objectives: To examine the effectiveness of targeting specific HIV and TB programme indicators for improvement using roving teams.

Method: We conducted a cluster-randomised stepped-wedge evaluation of a TA support package focussing on clinical, managerial and pharmacy services in the Mopani district of the Limpopo province, South Africa (SA). Three roving teams delivered the intervention. Seventeen primary and community healthcare centres that had 400-600 patients on antiretroviral therapy (ART) were selected for inclusion. The TA package was implemented for six consecutive months across facilities until all had received the same level of support. Data were collected from the relevant health management information systems for 11 routine indicators.

Results: The mean proportion of PLWH screened for tuberculosis (TB) at ART initiation increased from 85.2% to 87.2% (P = 0.65). Rates of retention in care improved, with the mean proportion of patients retained in care at three months post-ART initiation increasing from 79.9% to 87.4% (P < 0.001) and from 70.3% to 77.7% (P < 0.01) after six months. Finally, the mean proportion of patients with TB who completed their treatment increased from 80.6% to 82.1% (P = 0.75).

Conclusion: Tailored TA interventions in SA using a standardised structure and process led to a significant improvement in retention-in-care rates and to non-significant improvements in the proportion of PLWH screened for TB and of those who completed their treatment.

以指标为重点的南非艾滋病毒方案技术援助:阶梯式评价。
背景:在低收入和中等收入国家缺乏关于技术援助(TA)干预措施的研究。当地环境的变化需要为TA量身定制的方法,这些方法是结构化的,可在各个干预地点复制,同时保持适应当地环境的灵活性。我们开发了一个系统的技术助理流程,使用多学科巡回小组为包括当地艾滋病毒服务在内的各个要素提供支持。目的:检查针对特定的艾滋病毒和结核病规划指标的有效性,以改进使用巡回小组。方法:我们对南非林波波省莫帕尼地区的临床、管理和药学服务的TA支持包进行了一项集群随机楔形评估。三个流动小组提供了干预措施。有400-600名患者接受抗逆转录病毒治疗的17个初级和社区保健中心被选中纳入研究。在各设施连续实施6个月,直至所有设施均获得相同水平的支援。从相关卫生管理信息系统中收集11项常规指标的数据。结果:在抗逆转录病毒治疗开始时,PLWH筛查结核(TB)的平均比例从85.2%上升到87.2% (P = 0.65)。护理留置率得到改善,art治疗开始后3个月留置患者的平均比例从79.9%增加到87.4% (P < 0.001), 6个月后从70.3%增加到77.7% (P < 0.01)。最后,结核患者完成治疗的平均比例从80.6%增加到82.1% (P = 0.75)。结论:在SA中使用标准化结构和过程的量身定制的TA干预导致了留用率的显着改善,并且在结核病筛查的PLWH比例和完成治疗的比例方面没有显着改善。
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来源期刊
CiteScore
2.80
自引率
11.80%
发文量
41
审稿时长
>12 weeks
期刊介绍: The Southern African Journal of HIV Medicine is focused on HIV/AIDS treatment, prevention and related topics relevant to clinical and public health practice. The purpose of the journal is to disseminate original research results and to support high-level learning related to HIV Medicine. It publishes original research articles, editorials, case reports/case series, reviews of state-of-the-art clinical practice, and correspondence.
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